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Grant: Team Grant: ERA-Net PerMed

Université Laval

$322,798.00

Patient stratification based on DNA repair functionality for cancer precision medicine

EF 2019-20

Résumé
Resistance to targeted therapies in an already enriched population is common. Consequently, a proportion of patients receive personalised cancer-treatments that are not effective and the disease progresses to a more advanced stage. Our main goal is to improve the selection of patients who are candidates to a targeted therapy. Specifically, this project will impact on refining the patient population that will mostly benefit from PARP inhibitors and thereby recommend the best treatment option and reduce health costs.
Programme
Team Grant: ERA-Net PerMed
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
406820
Name
Masson Jean-Yves
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
German Federal Ministry of Research, Technology and Space (Berlin); Fonds de recherche du Québec - Santé (FRQS); Instituto de Salud Carloss III (Spain); The French National Research Agency (France)
Instname2
Cancer Research
Theme2
Clinical
Prcname2
Special Cases
Projecttitle
Patient stratification based on DNA repair functionality for cancer precision medicine
Programtype2
Operating Grants
Orgnameinp2
Université Laval
Cihramount2
$322,798
Cihrequipment2
$0
Programname2
Team Grant: ERA-Net PerMed
Keyworddelim
Clinical Research
Abstract
Resistance to targeted therapies in an already enriched population is common. Consequently, a proportion of patients receive personalised cancer-treatments that are not effective and the disease progresses to a more advanced stage. Our main goal is to improve the selection of patients who are candidates to a targeted therapy. Specifically, this project will impact on refining the patient population that will mostly benefit from PARP inhibitors and thereby recommend the best treatment option and reduce health costs.
Competitiondate
201906
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Masson, Jean-Yves
Approvedterm
3 ans 0 mois
Cihrcontribution2
Institute of Genetics~ $24,198~ $0~Major Initiatives #3~ $298,600~ $0~