Grant: Team Grant: HIV/AIDS Comorbidities Prevention and Healthy Living - LOI
Centre hospitalier de l'Université de Montréal (CHUM)
$25,000.00
Discovering immune pathways to successful aging in HIV infection
EF 2017-18
Résumé
People living with HIV can now experience prolonged survival, yet studies show that they experience some age-related diseases earlier. In this project, we will try to discover how residual HIV viruses alter the immune system and lead to premature aging, in particular cardiovascular disease and frailty. We will try to establish how differently various immune disruptions lead to cardiovascular disease or frailty in men vs. women. We are hoping to identify new potential therapeutic targets that can lead to drug development to prevent unsuccessful aging in HIV.
Programme
Team Grant: HIV/AIDS Comorbidities Prevention and Healthy Living - LOI
Emplacement
Quebec, Canada
Type de bénéficiaire
Not-for-profit organization or charity
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
367837
Name
Durand Madeleine
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Clinical
Prcname2
HIV/AIDS Comorbidities Prevention and Healthy Living
Projecttitle
Discovering immune pathways to successful aging in HIV infection
Programtype2
Operating Grants
Orgnameinp2
Centre hospitalier de l'Université de Montréal (CHUM)
Cihramount2
$25,000
Cihrequipment2
$0
Programname2
Team Grant: HIV/AIDS Comorbidities Prevention and Healthy Living - LOI
Keyworddelim
Cardiovascular; Cohort Study; Frailty; Hiv; Immunology; Viral Reservoirs
Abstract
People living with HIV can now experience prolonged survival, yet studies show that they experience some age-related diseases earlier. In this project, we will try to discover how residual HIV viruses alter the immune system and lead to premature aging, in particular cardiovascular disease and frailty. We will try to establish how differently various immune disruptions lead to cardiovascular disease or frailty in men vs. women. We are hoping to identify new potential therapeutic targets that can lead to drug development to prevent unsuccessful aging in HIV.
Competitiondate
201706
Approvedterm2
0 yr 6 mths
Pinamesdelim
Durand, Madeleine; Margolese, Shari L; Bernard, Nicole F; Chartrand-Lefebvre, Carl; Chomont, Nicolas; Jenabian, Mohammad-Ali; Mansour, Samer; Tremblay, Cécile L; Tsoukas, Christos M
Approvedterm
0 an 6 mois
Cihrcontribution2
~ $25,000~ $0~
