Grant: Operating Grant

Our goal is to improve the clinical care and outcomes of children with nephrotic syndrome. Currently, nephrotic syndrome care is quite variable across Canada, and there are also gaps between best evidence and practice. These issues are potential barriers to optimizing health outcomes of children with nephrotic syndrome. In order to improve care and optimize outcomes, we will study a national cohort of children with nephrotic syndrome. We will characterize clinical features, treatments given and outcomes experienced by these children. We will examine whether variation in steroid exposure affects patients' relapse rates. We will also determine who and what drives variation in care by studying physicians who provide nephrotic syndrome care. The results of our study will ultimately lead to development of a best practice approach for treatment of nephrotic syndrome across Canada.