Grant: Operating Grant
McGill University
$781,151.00
Molecular mechanisms of Invasive Aspergillosis
EF 2013-14
Résumé
The mold Aspergillus fumigatus causes a severe, and often fatal pneumonia in patients whose immune systems do not function normally. We have identified a molecule that this mold uses as a glue to attach to and invade our cells. We will study this molecule to understand how it sticks to our cells. We will develop new tests to detect this glue in order to improve our ability to diagnose this infection. Finally, we will develop new treatments that interfere with this glue to improve survival in this deadly infection
Programme
Operating Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
304495
Name
Sheppard Donald C
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Microbiology & Infectious Diseases
Projecttitle
Molecular mechanisms of Invasive Aspergillosis
Programtype2
Operating Grants
Orgnameinp2
McGill University
Cihramount2
$781,151
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Adherence; Antifungals; Aspergillus Fumigatus; Biofilms; Diagnostics; Invasive Fungal Disease
Abstract
The mold Aspergillus fumigatus causes a severe, and often fatal pneumonia in patients whose immune systems do not function normally. We have identified a molecule that this mold uses as a glue to attach to and invade our cells. We will study this molecule to understand how it sticks to our cells. We will develop new tests to detect this glue in order to improve our ability to diagnose this infection. Finally, we will develop new treatments that interfere with this glue to improve survival in this deadly infection
Competitiondate
201403
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Sheppard, Donald C
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $781,151~ $0~
