Grant: Catalyst Grant: Invention and High-Risk, High-Benefit Research
University of British Columbia
$300,000.00
Establishment of a Novel High Throughput Conditional Gene Trapping System
EF 2009-10
Résumé
1) To develop innovative scientific approaches to generate genome-wide conditional gene trap mutations in murine
embryonic stem (ES) cells.
2) To develop efficient high-throughput approaches to identify the sites of gene trap insertion for each mutant conditional ES
cell clone.
3) To provide phenotypic evidence that the conditional gene trap mutations are amenable to the generation of animal models
of human disease.
Programme
Catalyst Grant: Invention and High-Risk, High-Benefit Research
Bénéficiaire
Emplacement
British Columbia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
202258
Name
Jefferies Wilfred A
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Genetics
Theme2
Biomedical
Prcname2
Inventions, Technologies, or High Risk Grants
Projecttitle
Establishment of a Novel High Throughput Conditional Gene Trapping System
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
Catalyst Grant: Invention and High-Risk, High-Benefit Research
Keyworddelim
Conditional Knock-Out Mice; Es Cell; Gene Trap; Mouse Model
Abstract
1) To develop innovative scientific approaches to generate genome-wide conditional gene trap mutations in murine
embryonic stem (ES) cells.
2) To develop efficient high-throughput approaches to identify the sites of gene trap insertion for each mutant conditional ES
cell clone.
3) To provide phenotypic evidence that the conditional gene trap mutations are amenable to the generation of animal models
of human disease.
Competitiondate
201003
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Jefferies, Wilfred A
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~
