Grant: Foundation Grant
Ottawa Hospital Research Institute
$3,702,580.00
Investigating Virus-Host Interactions to Design Viral Anti Cancer Therapeutics
EF 2015-16
Résumé
Anti-cancer biotherapeutics built from viruses have begun to emerge as potential new ways to safely and effectively treat cancer. Our work has shown that viruses can be safely administered to cancer patients and in some cases can lead to complete tumor eradication even in advanced patients. This project is aimed at building on this work to create improved virus based therapeutics that alone, or in combination with other therapies, leads to complete responses in a larger proportion of patients. We will use large collections of viruses and explore their abilities to kill cancer cells with the goal of finding more effective therapeutics.
Programme
Foundation Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Other
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
333630
Name
Bell John C
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Foundation Grant
Projecttitle
Investigating Virus-Host Interactions to Design Viral Anti Cancer Therapeutics
Programtype2
Operating Grants
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$3,702,580
Cihrequipment2
$0
Programname2
Foundation Grant
Keyworddelim
Antiviral; Cancer; Crispr/Cas9; Genome Editing; Immunotherapy; Manufacturing; Next Generation Sequencing; Oncolytic Viruses; Screening; Vaccines
Abstract
Anti-cancer biotherapeutics built from viruses have begun to emerge as potential new ways to safely and effectively treat cancer. Our work has shown that viruses can be safely administered to cancer patients and in some cases can lead to complete tumor eradication even in advanced patients. This project is aimed at building on this work to create improved virus based therapeutics that alone, or in combination with other therapies, leads to complete responses in a larger proportion of patients. We will use large collections of viruses and explore their abilities to kill cancer cells with the goal of finding more effective therapeutics.
Competitiondate
201509
Approvedterm2
7 yrs 0 mth
Pinamesdelim
Bell, John C
Approvedterm
7 ans 0 mois
Cihrcontribution2
~ $3,702,580~ $0~
