Grant: Research Tools and Instruments - Category 1 (<$150,000)
Dalhousie University
$149,466.00
Multi-user fluorescence microscope for live cell imaging
EF 2012-13
Résumé
This proposal is to acquire an upgrade to an existing microscope that will allow 9 researchers and their trainees to monitor the changes in cellular activity in real-time. Powerful new techniques now allow researchers to attach fluorescent tags to individual proteins. Researchers can now follow individual proteins as they move through cells and interact with other proteins and cellular membranes using a fluorescence microscope with live cell imaging capability. This technology can be applied to understand how proteins interact with each other or respond to different treatments, and how these proteins work alone or together with other proteins to regulate or alter the normal function of cells. Studies performed with this live cell imaging system will provide important insights into normal cellular function and how cells respond to various stresses.
Programme
Research Tools and Instruments - Category 1 (<$150,000)
Bénéficiaire
Emplacement
Nova Scotia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
440381-2013
Name nom
Duncan, Roy
Department département
Microbiology and Immunology
Organization id
79
Institution établissement
Dalhousie University
Province en
Nova Scotia
Province fr
Nouvelle-Écosse
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2012
Competition year année de concours
2013
Award amount
149466
Program id
EQPEQ
Program name en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1501
Committee name en
Genes, Cells and Molecules
Committee name fr
Gènes, cellules et molécules
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
5100
Research subject group en
Cell biology
Research subject group fr
Biologie cellulaire
Research subject en
Cell biology
Research subject fr
Biologie cellulaire
Partie
1
Nb partie
1
Application title
Multi-user fluorescence microscope for live cell imaging
Keyword
NSERC
Application summary
This proposal is to acquire an upgrade to an existing microscope that will allow 9 researchers and their trainees to monitor the changes in cellular activity in real-time. Powerful new techniques now allow researchers to attach fluorescent tags to individual proteins. Researchers can now follow individual proteins as they move through cells and interact with other proteins and cellular membranes using a fluorescence microscope with live cell imaging capability. This technology can be applied to understand how proteins interact with each other or respond to different treatments, and how these proteins work alone or together with other proteins to regulate or alter the normal function of cells. Studies performed with this live cell imaging system will provide important insights into normal cellular function and how cells respond to various stresses.
