Grant: Discovery Grants Program - Individual

This proposed research program focusses on fundamental studies of collective dynamics and micromechanics in soft glassy systems using x-ray photon correlation spectroscopy (XPCS) with simultaneous in situ rheometry (rheo-XPCS). The proposed research program encompasses two complimentary thematic areas, each of which involves important fundamental research with potential for practical impact. Theme I, dynamical heterogeneity and nanoscale plasticity in driven soft glassy materials, addresses pressing questions about the nature of deformation and yielding at the microscale, a wide-open area of research that has technological implications to materials processing and failure. Theme II, collective dynamics, structural evolution and aging in biomolecular condensates, seeks a microscopic understanding of the mechanical and dynamical evolution of biological condensates, whose essential functional roles cell biology and pathology are now at the forefront of fundamental biosciences and biomedicine. Trainees will gain experience in XPCS research at several superlative international laboratory facilities and thereby will be at a distinct advantage for careers in academic and industrial materials research.