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Grant: Research Tools and Instruments

Memorial University of Newfoundland

$148,529.00

A multicomponent analytical gas chromatography for biological metabolites

EF 2022-23

Résumé
Gas chromatography (GC) is widely used for quantifying volatile and semi-volatile biological metabolites, and are usually equiped with a flame ionization detector (FID) and mass spectrometer (MS), which allows for accurate analysis of metabolites with high resolution. Moreover, when coupled with headspace sampling technique, it further enhances the accuracy of such platforms. Headspace GC-FID/MS analysis is well-suited for quantifying highly volatile and gaseous molecules, including short chain fatty acids, propanal, and other sulfur-containing compounds, which otherwise are challenging to measure in other chromatographic platforms. Here, we request a multicomponent GC system coupled with headspace analysis. Our team, comprising of top-notch scientists from early, mid, and well-established careers, requires the system for their NSERC-funded research to continue achieving world-class research goals. There is no functional GC system in the Department of Biochemistry and very limited headspace-capable GC system at Memorial University of Newfoundland. The applicants currently send their samples to other facilities, which causes significant delays in their research. The requested equipment will not only accelerates the team's research program but also provide a new avenue for HQP training and increase Canada's competitiveness in the field of food and nutritional research.
Programme
Research Tools and Instruments
Emplacement
Newfoundland and Labrador, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
RTI-2023-00592
Name nom
Mayengbam, Shyamchand
Department département
Biochemistry - Biochemistry
Organization id
89
Institution établissement
Memorial University of Newfoundland
Province en
Newfoundland and Labrador
Province fr
Terre-Neuve-et-Labrador
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2022
Competition year année de concours
2023
Award amount
148529
Program id
RTI
Program name en
Research Tools and Instruments
Program name fr
Outils et instruments de recherche
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
1602
Committee name en
Biological Systems and Functions (RTI)
Committee name fr
Systèmes et fonctions biologiques (OIR)
Area of application code
1201
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Life sciences (including biotechnology)
Area of application fr
Sciences de la vie (y compris biotechnologie)
Research subject code
6400
Research subject group en
Life sciences research related to human health and disease
Research subject group fr
Sciences de la vie liées à la santé publique et aux maladies humaines
Research subject en
Life sciences research related to human health and disease
Research subject fr
Sciences de la vie liées à la santé publique et aux maladies humaines
Installment
inst:1
Partie
1
Nb partie
1
Application title
A multicomponent analytical gas chromatography for biological metabolites
Application summary
Gas chromatography (GC) is widely used for quantifying volatile and semi-volatile biological metabolites, and are usually equiped with a flame ionization detector (FID) and mass spectrometer (MS), which allows for accurate analysis of metabolites with high resolution. Moreover, when coupled with headspace sampling technique, it further enhances the accuracy of such platforms. Headspace GC-FID/MS analysis is well-suited for quantifying highly volatile and gaseous molecules, including short chain fatty acids, propanal, and other sulfur-containing compounds, which otherwise are challenging to measure in other chromatographic platforms. Here, we request a multicomponent GC system coupled with headspace analysis. Our team, comprising of top-notch scientists from early, mid, and well-established careers, requires the system for their NSERC-funded research to continue achieving world-class research goals. There is no functional GC system in the Department of Biochemistry and very limited headspace-capable GC system at Memorial University of Newfoundland. The applicants currently send their samples to other facilities, which causes significant delays in their research. The requested equipment will not only accelerates the team's research program but also provide a new avenue for HQP training and increase Canada's competitiveness in the field of food and nutritional research.