Grant: Idea to Innovation

The PI is developing a non-invasive technique, based on Raman spectroscopy, for the detection of gout, the most common form of inflammatory arthritis. The current gold standard for diagnosing gout requires the aspiration of synovial fluid from the inflamed joint; the fluid is then analysed under polarized light microscopy for the presence of uric acid crystals. Due to the invasive nature of this process, the low success rate and the pain resulting to the subject, this procedure is only performed in 25% of sufferers. Clinicians prefer to rely on visual inspection. However, gout and the underlying problem of hyperuricemia, need to be in the advanced stages of the disease for this to be accurate. Early diagnosis would facilitate preventative medical treatment, thus alleviating symptoms and halting the insidious effects of hyperuricemia. The PI has developed a protocol which utilises a portable Raman spectroscope to identify uric acid crystals through the skin. the concept has been proven in a rudimentary animal model and the PI is now testing the protocol in a clinical setting. The PI is requesting funding to undertake market assessment on the utility of such a diagnostic. The work will be outsourced to McCarthy Consultants who will conduct an assessment based upon a discussion with a rheumatologist (identified by the client), secondary data available reflecting patient visits for the diagnosis and treatment of gout, evaluation of the provincial payment schemes covering diagnostic agents and procedures in the major provinces (Ontario & Quebec) and a review of the private insurance company payment policies regarding this type of technology. Once completed , the size and growth potential of the Canadian gout diagnosis and treatment marketplace will be identified.