Contribution: Industrial Research Assistance Program – Contributions to Firms
Mediphage Bioceuticals, Inc.
$75,000.00
Linear Covalently Closed DNA Ministring (msDNA) Product and Production Process Development
EF 2022-23 · 2023-02-01
Résumé
This project will optimize the ministring DNA™ (msDNA™) production process to improve yield and purity while also making the process more stable, robust, and resistant to supply chain disruption, while also making the materials safer in the eyes of regulatory agencies by eliminating antibiotic usage from upstream production. Additionally, this project will evaluate next generation msDNA™ constructs to improve the therapeutic effectiveness of the drug substance. In summary, the outcomes of this project will improve the msDNA™ product, the production process, and facilitate the smooth and rapid transition to large-scale production to support Mediphage's genetic medicine program.
Ministère
Programme
Industrial Research Assistance Program – Contributions to FirmsIndustrial Research Assistance Program-Contributions to Firms (lien de confiance élevée)
Bénéficiaire
Emplacement
Toronto|Toronto, Ontario, Canada
Type de bénéficiaire
For-profit organization
Numéro d'entreprise
788308328
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
Tel que publié
Agreement End Date
2023-09-30
Agreement Number
1001542
Agreement Start Date
2023-02-01
Agreement Title
Linear Covalently Closed DNA Ministring (msDNA) Product and Production Process Development
Agreement Title (French)
Développement d’un produit et d’un processus de production pour le ministring d’ADN linéaire fermé de manière covalente (msDNA)
Agreement Type
Contribution
Agreement Value
$75,000.00
Amendment Number
0
Coverage
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation. | Les projets des Contributions aux entreprises stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
This project will optimize the ministring DNA™ (msDNA™) production process to improve yield and purity while also making the process more stable, robust, and resistant to supply chain disruption, while also making the materials safer in the eyes of regulatory agencies by eliminating antibiotic usage from upstream production. Additionally, this project will evaluate next generation msDNA™ constructs to improve the therapeutic effectiveness of the drug substance. In summary, the outcomes of this project will improve the msDNA™ product, the production process, and facilitate the smooth and rapid transition to large-scale production to support Mediphage's genetic medicine program.
Description (French)
Ce projet optimisera le processus de production de ministring DNA™ (msDNA™) afin d’améliorer le rendement et la pureté tout en rendant le processus plus stable, robuste et résistant aux perturbations de la chaîne d’approvisionnement, tout en rendant les matériaux plus sûrs aux yeux des organismes de réglementation en éliminant l’utilisation d’antibiotiques dans la production en amont. En outre, ce projet évaluera les constructions msDNA™ de nouvelle génération pour améliorer l’efficacité thérapeutique de la substance médicamenteuse. En résumé, les résultats de ce projet amélioreront le produit msDNA™, le processus de production, et faciliteront la transition rapide et sans heurts vers une production à grande échelle pour soutenir le programme de médecine génétique de Mediphage.
Expected Results
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Expected Results (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Federal Riding
University--Rosedale
Federal Riding (French)
University--Rosedale
Federal Riding Number
35110
NAICS Code
54171
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Contributions to Firms
Program Name (French)
Programme d’aide à la recherche industrielle – Contributions aux entreprises
Program Purpose
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Program Purpose (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Recipient Business Number
788308328
Recipient City
Toronto|Toronto
Recipient Country
CA
Recipient Legal Name
Mediphage Bioceuticals, Inc.
Recipient Postal Code
M5G 0B7
Recipient Province or Territory
ON
Recipient Type
F
Reference Number
172-2022-2023-Q4-1001542
