Grant: Rapid Funding for DSEN Targeted Research

This study is focused on the cardiac safety of domperidone when used to improve lactation in breast-feeding women. This use of domperidone is currently used off-label, however, prescribed to an increasing number of women who experience difficulty lactating. The findings of this study will determine the cardiac safety of domperidone in this off-labeled use. Study Objectives: 1. Describe the use of domperidone in lactation clinics in four Canadian provinces. 2. Investigate the impact of clinical factors, including: medication dose, duration, pre-existing cardiac conditions, and concomitant medications on cardiac adverse effects. 3. Take ECG measurements pre- and post-medication to measure cardiac effects.