Grant: Canada Postdoctoral Research Award (CPRA) program
University of British Columbia
$140,000.00
Clinical correlation of the genomics of endometriosis: integrating germline and spatial approaches
EF 2025-26
Résumé
In Canada, 1 in 10 girls, women and unmeasured numbers of two-spirit, transgender & gender-diverse people live with endometriosis. This disease is defined as tissue that resembles tissue from inside the uterus, but which is growing outside the uterus. Endometriosis is a common cause of pelvic pain and infertility. The goal of my research is to use genetic data and imaging techniques and to correlate this data with pain and its underlying causes in endometriosis to identify potential new therapeutic targets. My particular focus is pain with sexual activity in endometriosis (called dyspareunia), which can be related to nerve growth occurring around endometriosis. I will work with patient partners to ensure this research is disseminated to the public. My research will help us understand the role of genetic differences in people with endometriosis, in terms of how they relate to symptoms, and their potential influence on the success of future treatments in endometriosis.
Programme
Canada Postdoctoral Research Award (CPRA) program
Bénéficiaire
Emplacement
British Columbia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
536782
Name
Lacouture Aurélie
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Gender and Health
Theme2
Biomedical
Prcname2
Canada Postdoctoral Research Award - B
Projecttitle
Clinical correlation of the genomics of endometriosis: integrating germline and spatial approaches
Programtype2
Fellowship Programs
Orgnameinp2
University of British Columbia
Cihramount2
$140,000
Cihrequipment2
$0
Programname2
Canada Postdoctoral Research Award (CPRA) program
Keyworddelim
Cyclic Immunofluorescence; Endometriosis; Gene Expression; Neurogenesis; Pain; Spatial Transcriptomics; Therapeutic Target; Tissue Micro-Array
Abstract
In Canada, 1 in 10 girls, women and unmeasured numbers of two-spirit, transgender & gender-diverse people live with endometriosis. This disease is defined as tissue that resembles tissue from inside the uterus, but which is growing outside the uterus. Endometriosis is a common cause of pelvic pain and infertility. The goal of my research is to use genetic data and imaging techniques and to correlate this data with pain and its underlying causes in endometriosis to identify potential new therapeutic targets. My particular focus is pain with sexual activity in endometriosis (called dyspareunia), which can be related to nerve growth occurring around endometriosis. I will work with patient partners to ensure this research is disseminated to the public. My research will help us understand the role of genetic differences in people with endometriosis, in terms of how they relate to symptoms, and their potential influence on the success of future treatments in endometriosis.
Competitiondate
202509
Approvedterm2
2 yrs 0 mth
Pinamesdelim
Lacouture, Aurélie
Approvedterm
2 ans 0 mois
Cihrcontribution2
~ $140,000~ $0~