Grant: Project Grant

Cardio-metabolic diseases such as heart attack, stroke and diabetes are leading causes of death in Canada. Our project aims to identify new blood biomarkers of cardio-metabolic diseases that directly contribute to disease risk. We will do so by integrating information from a comprehensive blood biomarker screen with genetic markers. This will enable us to determine if biomarkers are part of the mechanisms of disease, or merely bystanders. This distinction is important as blood biomarkers that directly or indirectly contribute to disease are more likely to provide unbiased estimates of disease risk and help tailor therapeutic strategies to match individual risk profiles. Blood biomarkers will be used to identify at-risk individuals and help develop new therapeutic interventions.