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Grant: Engage Grants Program

University of Prince Edward Island

$25,000.00

Reducing Inflammation in the Equine Athlete with Ahiflower Oil

EF 2016-17

Résumé
Oil rich in the n-3 fatty acid stearidonic acid (SDA) from the Ahiflower plant (Buglossoides arvensis) istrademarked and marketed for human use having achieved food approvals in the US and UK (with othercountries pending). The next steps in the commercialization of Ahiflower oil for Nature's Crops Internationalinclude developing and commercializing it as an omega-3 supplement for animals, including horses.Arthritis is the most significant cause of lameness in horses and can lead to the early retirement of otherwisehealthy animals. Previous research in a variety of species has shown that long-chain n-3 polyunsaturated fattyacids (PUFA) have the potential to mitigate the pain and inflammation caused by arthritis, as well as possiblyslowing down joint degradation. In arthritic horses, supplementation with these PUFA resulted in an increasedstride length and reduced inflammatory markers in horses. At present, the most effective long-chain PUFAsource is marine oil but it is expensive, not sustainable, and quite unpalatable to horses. Ahiflower oil isunique in that it contains the precursor fatty acid, SDA (stearidonic acid), that can convert to the long-chainPUFA in the body more directly than the precursor fatty acids in other oils such as flax. We want to investigatethe use of ahiflower oil in racing Standardbred horses to increase the amount of long-chain PUFA in theirsystems and to reduce the amount of inflammation they suffer. We will compare dietary supplementation ofahiflower oil with flax and corn oil to racing horses and measure differences in fatty acid composition of bloodand several inflammatory markers.Ahiflower oil, produced and marketed by Nature's Crops International, may prove to be a healthy, economicaland more sustainable alternative to marine oil sources and a more effective source of long-chainpolyunsaturated fatty acids than other plant sources. We anticipate that results from this preliminary study willlead to increased market potential for ahiflower oil sales, thereby resulting in increased manufacturing andsignificantly increasing sales and revenue.
Programme
Engage Grants Program
Emplacement
Prince Edward Island, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
492424-2015
Name nom
RodriguezLecompte, JuanCarlos
Department département
Pathology and Microbiology
Organization id
88
Institution établissement
University of Prince Edward Island
Province en
Prince Edward Island
Province fr
?le-du-Prince-Édouard
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2016
Competition year année de concours
2015
Award amount
25000
Program id
EGP
Program name en
Engage Grants Program
Program name fr
Programme de subventions d'engagement partenariat
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1551
Committee name en
Atlantic Internal Decision Committee
Committee name fr
Comité de décision interne pour l'Atlantique
Area of application code
101
Area of application group en
Agriculture and primary food production
Area of application group fr
Agriculture et produits alimentaires primaires
Area of application en
Animal production and animal primary products
Area of application fr
Production animale et produits animaux primaires
Research subject code
5504
Research subject group en
Animal biology
Research subject group fr
Biologie animale
Research subject en
Animal physiology and metabolism
Research subject fr
Physiologie et métabolisme des animaux
Partie
1
Nb partie
1
Application title
Reducing Inflammation in the Equine Athlete with Ahiflower Oil
Keyword
NSERC
Application summary
Oil rich in the n-3 fatty acid stearidonic acid (SDA) from the Ahiflower plant (Buglossoides arvensis) istrademarked and marketed for human use having achieved food approvals in the US and UK (with othercountries pending). The next steps in the commercialization of Ahiflower oil for Nature's Crops Internationalinclude developing and commercializing it as an omega-3 supplement for animals, including horses.Arthritis is the most significant cause of lameness in horses and can lead to the early retirement of otherwisehealthy animals. Previous research in a variety of species has shown that long-chain n-3 polyunsaturated fattyacids (PUFA) have the potential to mitigate the pain and inflammation caused by arthritis, as well as possiblyslowing down joint degradation. In arthritic horses, supplementation with these PUFA resulted in an increasedstride length and reduced inflammatory markers in horses. At present, the most effective long-chain PUFAsource is marine oil but it is expensive, not sustainable, and quite unpalatable to horses. Ahiflower oil isunique in that it contains the precursor fatty acid, SDA (stearidonic acid), that can convert to the long-chainPUFA in the body more directly than the precursor fatty acids in other oils such as flax. We want to investigatethe use of ahiflower oil in racing Standardbred horses to increase the amount of long-chain PUFA in theirsystems and to reduce the amount of inflammation they suffer. We will compare dietary supplementation ofahiflower oil with flax and corn oil to racing horses and measure differences in fatty acid composition of bloodand several inflammatory markers.Ahiflower oil, produced and marketed by Nature's Crops International, may prove to be a healthy, economicaland more sustainable alternative to marine oil sources and a more effective source of long-chainpolyunsaturated fatty acids than other plant sources. We anticipate that results from this preliminary study willlead to increased market potential for ahiflower oil sales, thereby resulting in increased manufacturing andsignificantly increasing sales and revenue.