Grant: Research Tools and Instruments
Institut national de la recherche scientifique
$149,742.00
Automated high resolution morphological and behavioural analysis system
EF 2022-23
Résumé
A multidisciplinary team of researchers with expertise in studying development, neurosciences physiology, toxicology, pharmacology, virology and behaviour in zebrafish is requesting funds for the purchase of an automated high-resolution video tracking and analysis system. Specifically, the requested state-of-the-art video-tracking system (Ramona MCAM) will be used to evaluate zebrafish morphology and behaviour at high resolution and high throughput. This innovative system will enable fast, unbiased, high throughput, accurate, and consistent video-aided measurements of a broad range of morphological and behavioural parameters to address both fundamental and applied questions in neurobiology, animal physiology, toxicology, pharmacology and virology. Specifically, the requested equipment will allow the applicants and their team to: 1) investigate molecular mechanisms in neuronal development in zebrafish and 2) investigate the effects of virus infection, biomaterials and endocrine disruptors on the development, neurodevelopment, physiology and behaviour of zebrafish larvae. Our HQP will be provided with an invaluable opportunity for the cutting-edge training needed for their respective research areas as well as in high-resolution imaging and complex behavioural data analysis. They will be highly sought after by academia, government, or industry research departments as research using zebrafish becomes more significant for biomedical modelling of disease, drug screening, and toxicological studies.
Programme
Research Tools and Instruments
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
RTI-2023-00487
Name nom
Patten, Kessen (Shunmoogum)
Department département
Armand Frappier Santé Biotechnologies, Centre - Armand Frappier Santé Biotechnologies, Centre
Organization id
56
Institution établissement
Institut national de la recherche scientifique
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2022
Competition year année de concours
2023
Award amount
149742
Program id
RTI
Program name en
Research Tools and Instruments
Program name fr
Outils et instruments de recherche
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
1602
Committee name en
Biological Systems and Functions (RTI)
Committee name fr
Systèmes et fonctions biologiques (OIR)
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
5500
Research subject group en
Animal biology
Research subject group fr
Biologie animale
Research subject en
Animal biology
Research subject fr
Biologie animale
Installment
inst:1
Partie
1
Nb partie
1
Application title
Automated high resolution morphological and behavioural analysis system
Application summary
A multidisciplinary team of researchers with expertise in studying development, neurosciences physiology, toxicology, pharmacology, virology and behaviour in zebrafish is requesting funds for the purchase of an automated high-resolution video tracking and analysis system. Specifically, the requested state-of-the-art video-tracking system (Ramona MCAM) will be used to evaluate zebrafish morphology and behaviour at high resolution and high throughput. This innovative system will enable fast, unbiased, high throughput, accurate, and consistent video-aided measurements of a broad range of morphological and behavioural parameters to address both fundamental and applied questions in neurobiology, animal physiology, toxicology, pharmacology and virology. Specifically, the requested equipment will allow the applicants and their team to: 1) investigate molecular mechanisms in neuronal development in zebrafish and 2) investigate the effects of virus infection, biomaterials and endocrine disruptors on the development, neurodevelopment, physiology and behaviour of zebrafish larvae. Our HQP will be provided with an invaluable opportunity for the cutting-edge training needed for their respective research areas as well as in high-resolution imaging and complex behavioural data analysis. They will be highly sought after by academia, government, or industry research departments as research using zebrafish becomes more significant for biomedical modelling of disease, drug screening, and toxicological studies.