Grant: Project Grant
Polytechnique Montréal
$761,176.00
Underpinning neuro-vascular decoupling in resting state networks of vascular diseases
EF 2019-20
Résumé
In this work we will investigate how resting brain function can be measured using blood imaging in the presence of vascular diseases. Changes in blood flow, volume and oxygenation in the brain have been used in many studies to infer how the brain works. However, when the plumbing used to carry blood is itself subject to dysfunction, there is a possibility that the relation between brain function and blood biomarkers changes. This study will investigate this relation by observing and manipulating neuronal function while measuring hemodynamics.
Programme
Project Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
418684
Name
Lesage Frédéric
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Medical Physics & Imaging
Projecttitle
Underpinning neuro-vascular decoupling in resting state networks of vascular diseases
Programtype2
Operating Grants
Orgnameinp2
Polytechnique Montréal
Cihramount2
$761,176
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Intrinsic Optical Imaging; Mri Imaging; Pulse Pressure; Resting State Networks
Abstract
In this work we will investigate how resting brain function can be measured using blood imaging in the presence of vascular diseases. Changes in blood flow, volume and oxygenation in the brain have been used in many studies to infer how the brain works. However, when the plumbing used to carry blood is itself subject to dysfunction, there is a possibility that the relation between brain function and blood biomarkers changes. This study will investigate this relation by observing and manipulating neuronal function while measuring hemodynamics.
Competitiondate
202003
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Lesage, Frédéric; Vanni, Matthieu P
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $761,176~ $0~
