Grant: Operating Grant
University of Toronto
$715,476.00
The Role of Deubiquitination Enzymes in Mitochondrial Quality Control
EF 2012-13
Résumé
Beyond being the powerhouse of the cell, mitochondria are critical machines that can determine the overall health of the cell, and when they malfunction, can contribute to the death of the cell. Mitochondrial dysfunction has been linked to many human diseases including Parkinson's disease. This proposal will uncover new aspects of mitochondrial biology and function and lead the way to future therapeutics for Parkinson's disease.
Programme
Operating Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
279843
Name
Mcquibban George A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Genetics
Theme2
Biomedical
Prcname2
Cell Physiology
Projecttitle
The Role of Deubiquitination Enzymes in Mitochondrial Quality Control
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$715,476
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Mitochondria; Neuronal Cell Death; Parkinson'S Disease; Quality Control
Abstract
Beyond being the powerhouse of the cell, mitochondria are critical machines that can determine the overall health of the cell, and when they malfunction, can contribute to the death of the cell. Mitochondrial dysfunction has been linked to many human diseases including Parkinson's disease. This proposal will uncover new aspects of mitochondrial biology and function and lead the way to future therapeutics for Parkinson's disease.
Competitiondate
201303
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Mcquibban, George A
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $715,476~ $0~
