Grant: CIHR New Investigator
Université Laval
$300,000.00
Tau protein in neurobiology: regulation and deregulation in vivo.
EF 2012-13
Résumé
My research proposal is to develop a program examining the regulation of tau function in the normal brain, its deregulation in the diseased brain, with an emphasis on Alzheimer's disease (AD), and potential treatments available to alleviate tau pathology.
Thus the proposal will focus on 3 main research directions, performed mainly in vivo:
- Molecular basis of tau regulation in vivo
- Impact of biological and environmental factors on AD pathogenesis
- Pharmacological treatments of AD pathology
Programme
CIHR New Investigator
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
268805
Name
Planel Emmanuel
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Biomedical
Prcname2
New Investigators C
Projecttitle
Tau protein in neurobiology: regulation and deregulation in vivo.
Programtype2
Salary Programs
Orgnameinp2
Université Laval
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
CIHR New Investigator
Keyworddelim
Alzheimer'S Disease; Biological Factors; Environmental Factors; Microtubules; Protein Aggregation; Tau Protein
Abstract
My research proposal is to develop a program examining the regulation of tau function in the normal brain, its deregulation in the diseased brain, with an emphasis on Alzheimer's disease (AD), and potential treatments available to alleviate tau pathology.
Thus the proposal will focus on 3 main research directions, performed mainly in vivo:
- Molecular basis of tau regulation in vivo
- Impact of biological and environmental factors on AD pathogenesis
- Pharmacological treatments of AD pathology
Competitiondate
201209
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Planel, Emmanuel
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~