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Grant: CIHR-ICRH Travel Awards - ICRH / Vascular pool

Université Laval

$1,405.00

Association of D-dimers with Left Ventricular Hypertrophy and Clinical Outcomes in Mild to Moderate Aortic Stenosis: Results from the PROGRESSA Study

EF 2023-24

Résumé
146 patients with mild or moderate aortic stenosis were included in this sub-analysis. Clinical and Doppler echocardiographic data were collected yearly over a period of 10 years. D-dimers levels were significantly associated with Left Ventricular hypertrophy. Over a median follow-up of 8.10 (5.57-9.94) years, 38 (26%) patients died. Higher D-dimer levels were associated with increased risk of all-cause mortality.The simple measure of this new blood biomarker could help to enhance risk stratification and optimize the timing of intervention in asymptomatic patients with aortic stenosis.
Programme
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
495409
Name
Abdoun Kathia
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
Association of D-dimers with Left Ventricular Hypertrophy and Clinical Outcomes in Mild to Moderate Aortic Stenosis: Results from the PROGRESSA Study
Programtype2
Undefined
Orgnameinp2
Université Laval
Cihramount2
$1,405
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Keyworddelim
Aortic Stenosis; D-Dimers; Left Ventricular Hypertrophy
Abstract
146 patients with mild or moderate aortic stenosis were included in this sub-analysis. Clinical and Doppler echocardiographic data were collected yearly over a period of 10 years. D-dimers levels were significantly associated with Left Ventricular hypertrophy. Over a median follow-up of 8.10 (5.57-9.94) years, 38 (26%) patients died. Higher D-dimer levels were associated with increased risk of all-cause mortality.The simple measure of this new blood biomarker could help to enhance risk stratification and optimize the timing of intervention in asymptomatic patients with aortic stenosis.
Competitiondate
202309
Approvedterm2
1 yr 0 mth
Pinamesdelim
Abdoun, Kathia
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,405~ $0~