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Grant: Project Grant

University of Alberta

$784,126.00

Improving reproducibility in experimental research by using shared data -a use case in spinal cord injury

EF 2022-23

Résumé
There is a well-recognized problem regarding the efficiency of biomedical research in producing treatments for medical conditions. Contributing to this are the challenges to reproduce and translate experimental therapies into medical practice. This is particularly true in highly complex medical contexts such as spinal cord injury (SCI), which is among the leading cause of severe chronic disability worldwide. Open science and data sharing have been suggested as one tool to address these challenges by increasing transparency, reducing reporting bias, and fostering development and discovery. The SCI community has developed the Open Data Commons (ODC) for SCI following the international recommendations that data must be FAIR (Findable, Accessible, Interoperable and Reusable). Besides the ODC hosting more than 190 datasets across different species and data types (e.g., demographics, treatments), the reuse of this data to realize the promises of data sharing is still lacking. In this project, we suggest reusing shared data to accelerate the translation of experimental treatments to medical implementation.
Programme
Project Grant
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
478655
Name
Fouad Karim
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Tri-Agency Interdisciplinary - CIHR TIR
Projecttitle
Improving reproducibility in experimental research by using shared data -a use case in spinal cord injury
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$784,126
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Fair Data Sharing; Improving Statistical Analysis; Neurotrauma; Reproducibility; Translation
Abstract
There is a well-recognized problem regarding the efficiency of biomedical research in producing treatments for medical conditions. Contributing to this are the challenges to reproduce and translate experimental therapies into medical practice. This is particularly true in highly complex medical contexts such as spinal cord injury (SCI), which is among the leading cause of severe chronic disability worldwide. Open science and data sharing have been suggested as one tool to address these challenges by increasing transparency, reducing reporting bias, and fostering development and discovery. The SCI community has developed the Open Data Commons (ODC) for SCI following the international recommendations that data must be FAIR (Findable, Accessible, Interoperable and Reusable). Besides the ODC hosting more than 190 datasets across different species and data types (e.g., demographics, treatments), the reuse of this data to realize the promises of data sharing is still lacking. In this project, we suggest reusing shared data to accelerate the translation of experimental treatments to medical implementation.
Competitiondate
202303
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Fouad, Karim; Torres Espín, Abel
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $784,126~ $0~