Grant: Summer Program in Aging

Human diseases like Amyotrophic lateral sclerosis (ALS), affecting an estimated 3,000 Canadians, are detrimental and currently do not have a cure. To understand how we can find therapies, we first need to understand the biology of how the disease works. This can be done by studying the key protein that is responsible for these detrimental effects in individuals. The proposed research aims to use the key protein involved, modify it under control conditions and finally, test how those modifications affect the protein's structure and behaviour. By understanding how modifying the key protein involved in ALS affects its structure and function, it will allow for the development of therapeutics that target them.