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Grant: Collaborative Health Research Projects (NSERC partnered)

University of Toronto

$677,527.00

A Wireless CMOS Device for Rapid Point-of-Care Diagnosis of Bacterial Infections and Antibiotic Susceptibility Profiling

EF 2013-14

Résumé
The Canadian Foundation for Infectious Diseases estimates that 25% of all physician visits are related to infectious diseases and result in a total cost of >$12billion annually for treatment and lost productivity. We have developed a disposable microchip that is able to identify and type live bacteria in less than ten minutes with no bacterial culturing steps required. This technology combines the specificity of viruses (phages) that infect and kill bacteria with the sensitivity of integrated electronic circuits to create a low-cost, portable detection system. The system can also be used to allow rapid antibiotic susceptibility profiling that would provide positive antibiotic stewardship.
Programme
Collaborative Health Research Projects (NSERC partnered)
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
296084
Name
Gulak Glenn
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Natural Sciences and Engineering Research Council of Canada (NSERC)
Instname2
Infection and Immunity
Theme2
Clinical
Prcname2
Collaborative Health Research Projects - NSERC Partnered
Projecttitle
A Wireless CMOS Device for Rapid Point-of-Care Diagnosis of Bacterial Infections and Antibiotic Susceptibility Profiling
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$677,527
Cihrequipment2
$0
Programname2
Collaborative Health Research Projects (NSERC partnered)
Keyworddelim
Antibiotic Susceptibility; Bacterial Pathogens; Bacteriophage; Cmos Isfet; Low-Cost Mass-Producible Disposable; Lysins; Phage Panel; Rapid Point-Of-Care Diagnostics; Single-Chip With No Microfluidic Packaging; Wireless Power And Data Transfer
Abstract
The Canadian Foundation for Infectious Diseases estimates that 25% of all physician visits are related to infectious diseases and result in a total cost of >$12billion annually for treatment and lost productivity. We have developed a disposable microchip that is able to identify and type live bacteria in less than ten minutes with no bacterial culturing steps required. This technology combines the specificity of viruses (phages) that infect and kill bacteria with the sensitivity of integrated electronic circuits to create a low-cost, portable detection system. The system can also be used to allow rapid antibiotic susceptibility profiling that would provide positive antibiotic stewardship.
Competitiondate
201310
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Gulak, Glenn; Navarre, William W
Approvedterm
3 ans 0 mois
Cihrcontribution2
Knowledge Translation Branch~ $677,527~ $0~