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Grant: Travel Awards - Institute Community Support

University of Toronto

$1,200.00

Impact of Ultra Fine Particles on Childhood Development of Lung Functions and Asthma, Results from Canadian Healthy Infant Longitudinal Development (CHILD) Study

EF 2014-15

Résumé
Many publications have shown the adverse effects of air pollution and development of young children. However, the exact nature of the relationship between ultra fine particles (UFP) and its impact on development of lung function and asthma in children is still not fully understood. In this paper we aim to use the Toronto cohort from the Canadian Healthy Infant Longitudinal Development (CHILD) Study combined with ultra fine particle data of Toronto over the period of 2008-2014 to identify and describe both acute and longitudinal effects of UFP on children. The outcomes measured are the development of lung functions over time and asthma. Bayesian modeling is applied to particle data to simulate spread and time trend and validated with reference data at key time points. The resulting particulate measurement is then applied to regression models to estimate the effects of UFP on PFT measurements. Logistic regression model is used to estimate the impact of UFP on development of childhood asthma.
Programme
Travel Awards - Institute Community Support
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
324404
Name
Chuang Junior
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Social / Cultural / Environmental / Population Health
Prcname2
Institute of Circulatory and Respiratory Health
Projecttitle
Impact of Ultra Fine Particles on Childhood Development of Lung Functions and Asthma, Results from Canadian Healthy Infant Longitudinal Development (CHILD) Study
Programtype2
Undefined
Orgnameinp2
University of Toronto
Cihramount2
$1,200
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Ics Travel Awards
Abstract
Many publications have shown the adverse effects of air pollution and development of young children. However, the exact nature of the relationship between ultra fine particles (UFP) and its impact on development of lung function and asthma in children is still not fully understood. In this paper we aim to use the Toronto cohort from the Canadian Healthy Infant Longitudinal Development (CHILD) Study combined with ultra fine particle data of Toronto over the period of 2008-2014 to identify and describe both acute and longitudinal effects of UFP on children. The outcomes measured are the development of lung functions over time and asthma. Bayesian modeling is applied to particle data to simulate spread and time trend and validated with reference data at key time points. The resulting particulate measurement is then applied to regression models to estimate the effects of UFP on PFT measurements. Logistic regression model is used to estimate the impact of UFP on development of childhood asthma.
Competitiondate
201501
Approvedterm2
1 yr 0 mth
Pinamesdelim
Chuang, Junior
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Circ &Respiratory Hlth~ $1,200~ $0~