Grant: Foundation Grant
McMaster University
$1,955,863.00
Energy Sensing and Metabolism: From Mechanisms to New Therapies
EF 2017-18
Résumé
The explosive increase in type 2 diabetes across Canada and around the world in all demographics and ethnicities poses a substantial risk not only to the individuals affected but to society at large given the huge economic burden of managing the serious events of the disease. It has been recognized for decades that there is a strong connection between type 2 diabetes and heart disease but despite substantial research there are very few treatments which effectively reduce the effects of type 2 diabetes on promoting heart disease. My research studies key molecules/proteins which control how the body uses energy and is developing and testing new medicines that specifically impact these proteins in liver and adipose tissue in order to treat people with type 2 diabetes.
Programme
Foundation Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
368954
Name
Steinberg Gregory R
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Biomedical
Prcname2
Foundation Grant
Projecttitle
Energy Sensing and Metabolism: From Mechanisms to New Therapies
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$1,955,863
Cihrequipment2
$0
Programname2
Foundation Grant
Keyworddelim
Cardiovascular Disease; De Novo Lipogenesis; Endocrinology; Energy Expenditure; Insulin Resistance; Metabolism; Non-Alcoholic Fatty Liver Disease (Nafld); Non-Alcoholic Steahepatitis; Obesity; Type 2 Diabetes
Abstract
The explosive increase in type 2 diabetes across Canada and around the world in all demographics and ethnicities poses a substantial risk not only to the individuals affected but to society at large given the huge economic burden of managing the serious events of the disease. It has been recognized for decades that there is a strong connection between type 2 diabetes and heart disease but despite substantial research there are very few treatments which effectively reduce the effects of type 2 diabetes on promoting heart disease. My research studies key molecules/proteins which control how the body uses energy and is developing and testing new medicines that specifically impact these proteins in liver and adipose tissue in order to treat people with type 2 diabetes.
Competitiondate
201709
Approvedterm2
7 yrs 0 mth
Pinamesdelim
Steinberg, Gregory R
Approvedterm
7 ans 0 mois
Cihrcontribution2
~ $1,955,863~ $0~
