Grant: Operating Grant
University of Manitoba
$804,160.00
Chronic Antibody Mediated Rejection: Identification of mechanisms and diagnostic proteins
EF 2013-14
Résumé
Antibody-mediated rejection is one of the major reasons why patients loose their kidney grafts after transplant. This project will determine which proteins are the targets of antibodies that cause antibody-mediated rejection. In addition novel diagnostic blood tests will be developed to detect antibody-mediated rejection prior to them causing the kidney to malfunction or sustain damage which cannot be repaired. This early detection may allow for clinicians to intervene early and thereby improve transplant and patient survival.
Programme
Operating Grant
Bénéficiaire
Emplacement
Manitoba, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
290406
Name
Nickerson Peter W
Region
Manitoba
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
Clinical Investigation - C: Digestive, Endocrine and Excretory Systems
Projecttitle
Chronic Antibody Mediated Rejection: Identification of mechanisms and diagnostic proteins
Programtype2
Operating Grants
Orgnameinp2
University of Manitoba
Cihramount2
$804,160
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Antibody Mediated Rejection; Biomarkers; Chemokines; Proteomics; Transplantation
Abstract
Antibody-mediated rejection is one of the major reasons why patients loose their kidney grafts after transplant. This project will determine which proteins are the targets of antibodies that cause antibody-mediated rejection. In addition novel diagnostic blood tests will be developed to detect antibody-mediated rejection prior to them causing the kidney to malfunction or sustain damage which cannot be repaired. This early detection may allow for clinicians to intervene early and thereby improve transplant and patient survival.
Competitiondate
201309
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Nickerson, Peter W
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $804,160~ $0~
