Grant: Operating Grant: SPOR iCT Rewarding Success - Development Grants
Vancouver Island Health Authority
$100,000.00
Improving Treatment Outcomes and Value for Recurrent Clostridium difficile Infection through a Platform Adaptive Trial
EF 2017-18
Résumé
The impact of recurrent C Diff (rCD) infection is debilitating, and disrupts the lives of patients and their families. Current standard treatments for rCD are only 40% effective. We propose to compare five different treatments for rCD, including freeze-dried fecal microbiota transplant (FMT), which is very effective but not widely accessible in Canada. Freeze-dried FMT offers significantly higher cure rates than current standard treatments, and can expand access to treatment while reducing costs and improving quality of life and productivity. We will identify which of the five treatments is the most effective and beneficial for patients and for the healthcare system.
Programme
Operating Grant: SPOR iCT Rewarding Success - Development Grants
Bénéficiaire
Emplacement
British Columbia, Canada
Type de bénéficiaire
Government
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
378818
Name
Lee Christine H
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Clinical
Prcname2
SPOR iCT Rewarding Success - Phase 2: Ideathon
Projecttitle
Improving Treatment Outcomes and Value for Recurrent Clostridium difficile Infection through a Platform Adaptive Trial
Programtype2
Operating Grants
Orgnameinp2
Vancouver Island Health Authority
Cihramount2
$100,000
Cihrequipment2
$0
Programname2
Operating Grant: SPOR iCT Rewarding Success - Development Grants
Keyworddelim
Disease Control; Gastroenterology; Infectious Diseases; Patient-Oriented Research; Platform Adaptive Trial; Public Health
Abstract
The impact of recurrent C Diff (rCD) infection is debilitating, and disrupts the lives of patients and their families. Current standard treatments for rCD are only 40% effective. We propose to compare five different treatments for rCD, including freeze-dried fecal microbiota transplant (FMT), which is very effective but not widely accessible in Canada. Freeze-dried FMT offers significantly higher cure rates than current standard treatments, and can expand access to treatment while reducing costs and improving quality of life and productivity. We will identify which of the five treatments is the most effective and beneficial for patients and for the healthcare system.
Competitiondate
201802
Approvedterm2
1 yr 0 mth
Pinamesdelim
Lee, Christine H; Andersen, Joan; Peljhan, Marko; Roy, Hannah J; Yercha, Wayne; Kim, Peter T; Steiner, Theodore S; Zhang, Wei
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $100,000~ $0~
