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Grant: Foundation Grant

McMaster University

$4,246,166.00

Antibiotic resistance, discovery and biosynthesis

EF 2015-16

Résumé
Antibiotic resistance is arguably the health care challenge of our time, threatening to roll back over a century of advances in medicine. My research program strives to address the resistance crisis by exploring the mechanisms and origins of drug resistance and discovering new molecules and strategies that can be applied in drug discovery or management of our existing drugs. I have been working in this field for over 25 years and have established a laboratory that has international recognition as a leader and innovator in drug resistance and discovery. The vision of the lab is to build on this success and tackle some of the most challenging issues in antibiotics, including how to source new drug candidates, how to protect the ones we have, and how to predict and manage the emergence of new resistance elements.
Programme
Foundation Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
333810
Name
Wright Gerard D
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Foundation Grant
Projecttitle
Antibiotic resistance, discovery and biosynthesis
Programtype2
Operating Grants
Orgnameinp2
McMaster University
Cihramount2
$4,246,166
Cihrequipment2
$0
Programname2
Foundation Grant
Keyworddelim
Bacteria; Chemical Biology; Drug Discovery; Enzymology; Fungi; High Throughput Screening; Infection; Natrual Products; Pathogenesis; Synthetic Biology
Abstract
Antibiotic resistance is arguably the health care challenge of our time, threatening to roll back over a century of advances in medicine. My research program strives to address the resistance crisis by exploring the mechanisms and origins of drug resistance and discovering new molecules and strategies that can be applied in drug discovery or management of our existing drugs. I have been working in this field for over 25 years and have established a laboratory that has international recognition as a leader and innovator in drug resistance and discovery. The vision of the lab is to build on this success and tackle some of the most challenging issues in antibiotics, including how to source new drug candidates, how to protect the ones we have, and how to predict and manage the emergence of new resistance elements.
Competitiondate
201509
Approvedterm2
7 yrs 0 mth
Pinamesdelim
Wright, Gerard D
Approvedterm
7 ans 0 mois
Cihrcontribution2
~ $4,246,166~ $0~