Grant: CIHR - ICR / Cancer Research Society Partnership - Res. Grants - Breast Cancer

Inflammatory Breast Cancer (IBC) is a rare type of breast cancer that is associated with an extremely poor prognosis. There are currently not any therapies designed to target this special type of breast cancer. We have found that this cancer may be driven by a protein (RIPK2) that is normally used by the immune system. This grant will explore how RIPK2 may promote IBC progression and will determine whether a drug currently being tested for the treatment of inflammatory bowel diseases may be repurposed to treat IBCs. This would reveal a desperately needed therapy for a cancer for which there are few effective therapeutic options.