Grant: Operating Grant
Polytechnique Montréal
$554,138.00
Microscopic underpinnings of brain oxygen delivery with aging.
EF 2012-13
Résumé
In this project we will investigate the microscopic mechanisms associated with oxygen delivery to the brain and their changes with age and disease. Using new technological advances based on two-photon microscopy and optical coherence tomography, imaging of the microscopic distribution of oxygen will be performed and related to changes in blood flow within the micro-vasculature. As a last step, the impact of our results for clinical imaging and disease prevention will be investigated.
Programme
Operating Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
279039
Name
Lesage Frédéric
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Aging
Theme2
Biomedical
Prcname2
Medical Physics & Imaging
Projecttitle
Microscopic underpinnings of brain oxygen delivery with aging.
Programtype2
Operating Grants
Orgnameinp2
Polytechnique Montréal
Cihramount2
$554,138
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Aging; Atherosclerosis; Fmri; Micro-Vasculature; Oxygen Delivery; Two-Photon Microscopy
Abstract
In this project we will investigate the microscopic mechanisms associated with oxygen delivery to the brain and their changes with age and disease. Using new technological advances based on two-photon microscopy and optical coherence tomography, imaging of the microscopic distribution of oxygen will be performed and related to changes in blood flow within the micro-vasculature. As a last step, the impact of our results for clinical imaging and disease prevention will be investigated.
Competitiondate
201303
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Lesage, Frédéric
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $554,138~ $0~
