Grant: Operating Grant
Université de Montréal
$679,767.00
In vivo regulation of mitosis in stem cells
EF 2010-11
Résumé
Stem cells are the basis of life. As an embryo, stem cells develop into the multitude of diverse tissues in the body. In adults, stem cells are critical for maintaining the body; for instance the red blood cells in your body (about 4% of your body mass) now will be 100% different in about a month. On the other hand, misregulation of stem cell divisions leads to cancer. In this proposal, we will work to understand the fundamental properties of stem cell divisions in a living organism. Our well will identify new pathways to regulate stem cell proliferation as well as means to stop cancer stem cell divisions.
Programme
Operating Grant
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
224599
Name
Maddox Paul S
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Developmental Biology
Projecttitle
In vivo regulation of mitosis in stem cells
Programtype2
Operating Grants
Orgnameinp2
Université de Montréal
Cihramount2
$679,767
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Caenorhabditis Elegans; Cancer Stem Cells; Germline Development; Live Imaging; Mitosis; Polarity; Stem Cell Division
Abstract
Stem cells are the basis of life. As an embryo, stem cells develop into the multitude of diverse tissues in the body. In adults, stem cells are critical for maintaining the body; for instance the red blood cells in your body (about 4% of your body mass) now will be 100% different in about a month. On the other hand, misregulation of stem cell divisions leads to cancer. In this proposal, we will work to understand the fundamental properties of stem cell divisions in a living organism. Our well will identify new pathways to regulate stem cell proliferation as well as means to stop cancer stem cell divisions.
Competitiondate
201103
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Maddox, Paul S; Labbe, Jean-Claude
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $679,767~ $0~
