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Grant: Strategic Projects - Group

University of Western Ontario

$144,000.00

Genetic pest control: plant-generated RNAi gene knockouts in agricultural pest

EF 2006-07

Résumé
Application of chemical pesticides in agriculture represents one of crucial causes of environmental pollution, destruction of wildlife and introduction of known carcinogens in human food chain. Currently in Canada 937 tons of pesticides are applied, which amounts to 49.8 kg per hectare. Even though the cost of pesticides itself is $1.3 billions, estimated environmental and societal cost exceeds $4 billions. Thus, it is imperative to develop alternative, environmentally friendly, pest control approaches. In our application we propose to develop novel genetic pest control using naturally occurring RNA interference mechanism as a method for the pest control. We are combining our previous genomic work on model pest species spider mite Tetranychus urticae with genetics and genomics of model plant Arabidopsis to engineer plants that will terminate pest development by blocking unique genes in spider mite. Using this approach in combination with carefully designed environmental tests we propose to develop a novel pest control method based on non-toxic molecules that could be in future transferred to agricultural crops. This approach has a potential to reduce environmental pollution and result in production of healthy food.
Programme
Strategic Projects - Group
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
322206-2005
Name nom
Grbic, Miodrag
Department département
Biology
Organization id
36
Institution établissement
University of Western Ontario
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2006
Competition year année de concours
2005
Award amount
144000
Program id
STPGP
Program name en
Strategic Projects - Group
Program name fr
Projets stratégiques - De groupe
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1002
Committee name en
Strategic Projects Selection Panel - Biosciences B
Committee name fr
Comité de sélection des projets stratégiques - biosciences B
Area of application code
1201
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Life sciences (including biotechnology)
Area of application fr
Sciences de la vie (y compris biotechnologie)
Research subject code
5009
Research subject group en
Genetics
Research subject group fr
Génétique
Research subject en
Genetic engineering
Research subject fr
Génie génétique
Partie
2
Nb partie
3
Application title
Genetic pest control: plant-generated RNAi gene knockouts in agricultural pest
Keyword
NA
Application summary
Application of chemical pesticides in agriculture represents one of crucial causes of environmental pollution, destruction of wildlife and introduction of known carcinogens in human food chain. Currently in Canada 937 tons of pesticides are applied, which amounts to 49.8 kg per hectare. Even though the cost of pesticides itself is $1.3 billions, estimated environmental and societal cost exceeds $4 billions. Thus, it is imperative to develop alternative, environmentally friendly, pest control approaches. In our application we propose to develop novel genetic pest control using naturally occurring RNA interference mechanism as a method for the pest control. We are combining our previous genomic work on model pest species spider mite Tetranychus urticae with genetics and genomics of model plant Arabidopsis to engineer plants that will terminate pest development by blocking unique genes in spider mite. Using this approach in combination with carefully designed environmental tests we propose to develop a novel pest control method based on non-toxic molecules that could be in future transferred to agricultural crops. This approach has a potential to reduce environmental pollution and result in production of healthy food.