Grant: Project Grant
Centre for Addiction and Mental Health (Toronto)
$1,315,800.00
Investigating the Interplay between FAAH and Opioid Misuse in Chronic Pain
EF 2025-26
Résumé
Chronic pain affects millions of Canadians and significantly contributes to the opioid crisis. The proposed neuroimaging study investigates whether brain level of FAAH, a key enzyme that controls levels of the cannabis-like endogenous cannabinoid anandamide, relates to opioid use disorder in people with chronic pain. Understanding the role of FAAH in people with chronic pain and opioid use disorder may lead to the development of new ways to target and treat pain and reduce the risk of addiction, ultimately helping millions of people live better lives.
Programme
Project Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
533525
Name
Boileau Isabelle
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Clinical
Prcname2
Behavioural Sciences - B: Clinical Behavioural Sciences
Projecttitle
Investigating the Interplay between FAAH and Opioid Misuse in Chronic Pain
Programtype2
Operating Grants
Orgnameinp2
Centre for Addiction and Mental Health (Toronto)
Cihramount2
$1,315,800
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Chronic Non-Cancer Pain; Endocannabinoid System; Fatty Acid Amide Hydrolase (Faah); Opioid Use Disorder; Positron Emission Tomography
Abstract
Chronic pain affects millions of Canadians and significantly contributes to the opioid crisis. The proposed neuroimaging study investigates whether brain level of FAAH, a key enzyme that controls levels of the cannabis-like endogenous cannabinoid anandamide, relates to opioid use disorder in people with chronic pain. Understanding the role of FAAH in people with chronic pain and opioid use disorder may lead to the development of new ways to target and treat pain and reduce the risk of addiction, ultimately helping millions of people live better lives.
Competitiondate
202509
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Boileau, Isabelle; Le Foll, Bernard; Moayedi, Massieh
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $1,315,800~ $0~
