Grant: Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI
University of British Columbia
$0.00
Multifunctional Targeted Biodegradable Nanodevices for Molecular Imaging and Multidrug Therapy
EF 2009-10
Résumé
Lung cancer is one of the leading cause of the death in world. With the current medical intervention, only 15% people survive 5 years after the initial diagnosis. There is also significant toxicity associated with current anticancer agents as normal tissues also killed along with cancer tissues during the treatment. Thus it is important to develop novel agents which can identify tumour sites and cure the cancer. In this project, we are developing a novel nanotechnology based new generation device for the delivery of anticancer drugs only to tumour sites and see them simultaneously. This novel nanodevice is based on a bio-degradable polymer developed recently in our laboratory. Drug loaded nanodevice will be attached with a specific agent that directly go to the tumour site when injected in the blood stream of human body without affecting other organs. This intelligent targeting in complex body environment will significantly reduce the side effects associated with the current anti-cancer treatments. This will be first the method to treat tumour growth as well see them receding in real time. This revolutionary next generation nanodevice platform will change current treatment methods, and will have broad applicability in treating many other cancers and other diseases.
Programme
Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI
Bénéficiaire
Emplacement
British Columbia, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
196715
Name
Brooks Donald E
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Emerging Team Grant: Regenerative Medicine and Nanomedicine
Projecttitle
Multifunctional Targeted Biodegradable Nanodevices for Molecular Imaging and Multidrug Therapy
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$0
Cihrequipment2
$0
Programname2
Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI
Keyworddelim
Angiogenisis; Bio-Degradable Polyglycerols; Multi Drug Therapy; Nanodevices; Tumor Imaging; Tumor Targeting
Abstract
Lung cancer is one of the leading cause of the death in world. With the current medical intervention, only 15% people survive 5 years after the initial diagnosis. There is also significant toxicity associated with current anticancer agents as normal tissues also killed along with cancer tissues during the treatment. Thus it is important to develop novel agents which can identify tumour sites and cure the cancer. In this project, we are developing a novel nanotechnology based new generation device for the delivery of anticancer drugs only to tumour sites and see them simultaneously. This novel nanodevice is based on a bio-degradable polymer developed recently in our laboratory. Drug loaded nanodevice will be attached with a specific agent that directly go to the tumour site when injected in the blood stream of human body without affecting other organs. This intelligent targeting in complex body environment will significantly reduce the side effects associated with the current anti-cancer treatments. This will be first the method to treat tumour growth as well see them receding in real time. This revolutionary next generation nanodevice platform will change current treatment methods, and will have broad applicability in treating many other cancers and other diseases.
Competitiondate
200911
Approvedterm2
0 yr 0 mth
Pinamesdelim
Brooks, Donald E; Bally, Marcel B; Benard, Francois
Approvedterm
0 an 0 mois