Grant: Rapid Funding for DSEN Targeted Research
Ottawa Hospital Research Institute
$96,943.00
The risk of elevated prolactin levels in pediatric patients exposed to risperidone and other antipsychotics for the treatment of schizophrenia and other schizophrenia spectrum disorders: a network meta-analysis
EF 2012-13
Résumé
The use of antipsychotic medications in children and adolescents has increased substantially in the past decade. Although these medications can relieve symptoms for those suffering from schizophrenia and related conditions, they may increase a blood protein called prolactin. High blood prolactin can result in conditions called gynecomastia, galactorrhea, infertility, menstrual irregularities, sexual dysfunction, decreased libido, or acne. However, we do not completely understand the extent of these side effects in children and adolescents. Therefore, we propose to study and compare the prolactin-related side effects of each of the antipsychotic medications.
Programme
Rapid Funding for DSEN Targeted Research
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Other
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
278132
Name
Moher David
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Health Services and Policy Research
Theme2
Clinical
Prcname2
Rapid Funding for DSEN Targeted Research
Projecttitle
The risk of elevated prolactin levels in pediatric patients exposed to risperidone and other antipsychotics for the treatment of schizophrenia and other schizophrenia spectrum disorders: a network meta-analysis
Programtype2
Miscellaneous Programs
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$96,943
Cihrequipment2
$0
Programname2
Rapid Funding for DSEN Targeted Research
Keyworddelim
Antipsychotic Medications; Multiple Treatment Comparison; Network Meta-Analysis; Pediatic Patients; Prolactin-Related Adverse Events; Risperidone
Abstract
The use of antipsychotic medications in children and adolescents has increased substantially in the past decade. Although these medications can relieve symptoms for those suffering from schizophrenia and related conditions, they may increase a blood protein called prolactin. High blood prolactin can result in conditions called gynecomastia, galactorrhea, infertility, menstrual irregularities, sexual dysfunction, decreased libido, or acne. However, we do not completely understand the extent of these side effects in children and adolescents. Therefore, we propose to study and compare the prolactin-related side effects of each of the antipsychotic medications.
Competitiondate
201301
Approvedterm2
1 yr 0 mth
Pinamesdelim
Moher, David; Mills, Edward J
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $96,943~ $0~
