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Grant: Applied Research Tools and Instruments Grants

Cégep de Lévis

$200,000.00

Automation of Flexible Immunostaining Modalities for High Throughput Histopathology in Applied Research Projects

EF 2024-25

Résumé
This Applied Research Tools and Instruments grant aims at acquiring a flexible research-adapted immunostaining system to automate histopathological analysis in TransBIOTech applied research and development projects. This system would replace manual immunostaining techniques which are particularly labour-intensive for the research staff. Moreover, this system would dock directly with the current flow of histopathological analysis platform where the acquisition of microscopical images on histological specimens is already automated. This acquisition would significantly improve the efficiency and robustness of this limiting step in the numerous applied research projects involving immunostaining analysis conducted at TransBIOTech. Moreover, it would strongly benefit to the training of the numerous trainees and students that TransBIOTech supervise by exposing them to state-of-the-art technologies. Histology being among the lengthiest analyses in typical research projects performed at TransBIOTech, being capable of this improved pace would positively impact several of the industrial partners in the field of in vivo pharmacology. As critical decisions in a preclinical product pipeline are often based on preclinical experimental results, expediting the time-to-results would have a substantial effect on the campaign duration of industrial partners in their product development, consequently hastening their commercialization rates. Automated immunostaining modalities would thus benefit partner-oriented projects and leverage their innovation potential by improving results quality, getting answers faster but also by allowing TransBIOTech technicians to perform several experiments simultaneously, therefore increasing the productivity without compromising the employee well-being.
Programme
Applied Research Tools and Instruments Grants
Bénéficiaire
Emplacement
Quebec, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
CARTI-2024-00004
Name nom
Couture, Frédéric
Department département
TransBIOTech, Centre de Recherche et Transfert Technologique en Biotechnologies - Cégep de Lévis
Organization id
101409
Institution établissement
Cégep de Lévis
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2024
Competition year année de concours
2024
Award amount
200000
Program id
CARTI
Program name en
Applied Research Tools and Instruments Grants
Program name fr
Subventions d'outils et d'instruments de recherche appliquée
Group en
RESEARCH PARTNERSHIPS
Group fr
PARTENARIATS DE RECHERCHE
Committee code
CCARTI-2024
Committee name en
ARTI Review Committee
Committee name fr
Comité d’évaluation OIRA
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
9999
Research subject group en
Not available
Research subject group fr
Non disponible
Research subject en
Not available
Research subject fr
Non disponible
Field of research list codes
RDF3010599
Field of research list names en
Pharmacology and pharmaceutical sciences, n.e.c.
Field of research list names fr
Pharmacologie et sciences pharmaceutiques, n.c.a.
Socioeconomic objective list codes
RDS10701
Socioeconomic objective list names en
Human health procedures and pharmaceutical treatments
Socioeconomic objective list names fr
Interventions et traitements pharmaceutiques ayant trait à la santé humaine
Application title
Automation of Flexible Immunostaining Modalities for High Throughput Histopathology in Applied Research Projects
Keywords
Histology; Immunohistochemistry; Immuno-oncology; Toxicology; Immunofluorescence
Application summary
This Applied Research Tools and Instruments grant aims at acquiring a flexible research-adapted immunostaining system to automate histopathological analysis in TransBIOTech applied research and development projects. This system would replace manual immunostaining techniques which are particularly labour-intensive for the research staff. Moreover, this system would dock directly with the current flow of histopathological analysis platform where the acquisition of microscopical images on histological specimens is already automated. This acquisition would significantly improve the efficiency and robustness of this limiting step in the numerous applied research projects involving immunostaining analysis conducted at TransBIOTech. Moreover, it would strongly benefit to the training of the numerous trainees and students that TransBIOTech supervise by exposing them to state-of-the-art technologies. Histology being among the lengthiest analyses in typical research projects performed at TransBIOTech, being capable of this improved pace would positively impact several of the industrial partners in the field of in vivo pharmacology. As critical decisions in a preclinical product pipeline are often based on preclinical experimental results, expediting the time-to-results would have a substantial effect on the campaign duration of industrial partners in their product development, consequently hastening their commercialization rates. Automated immunostaining modalities would thus benefit partner-oriented projects and leverage their innovation potential by improving results quality, getting answers faster but also by allowing TransBIOTech technicians to perform several experiments simultaneously, therefore increasing the productivity without compromising the employee well-being.