Grant: Idea to Innovation
University of Prince Edward Island
$125,000.00
Nanofreeze Solutions for Organoids and Genetic Material Storage
EF 2023-24
Résumé
This project aims to develop new methods for prolonged storage of tissues and genetic materials. The storage of cells, tissues and genetic material is desirable to improve human health, for biobanking and to develop assisted reproductive technology methods. However, current methods being used for storage of tissues and genetic material involve chemical that can cause toxicity and change the genetic profile of stored materials. Therefore, there is a need to find alternative methods that are non-toxic and inert and can be used for storage of tissues and genetic materials for health applications. We have recently developed a vitamin B5 based technology that has shown excellent capacity to store mammalian cells under freezing conditions. In this project, we will optimize this technology further to produce formulations that can successfully store genetic materials and tissues for various applications.
Programme
Idea to Innovation
Bénéficiaire
Emplacement
Prince Edward Island, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
586907-2023
Name nom
Ahmed, Marya M
Department département
Chemistry
Organization id
88
Institution établissement
University of Prince Edward Island
Province en
Prince Edward Island
Province fr
Île-du-Prince-Édouard
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2023
Award amount
125000
Program id
I2IPJ
Program name en
Idea to Innovation
Program name fr
De l'idée à l'innovation
Group en
RESEARCH PARTNERSHIPS
Group fr
PARTENARIATS DE RECHERCHE
Committee code
96
Committee name en
RPP Internal Decision Cttee
Committee name fr
Cté de décision interne - PPR
Area of application code
1208
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Materials sciences
Area of application fr
Sciences des matériaux
Research subject code
1902
Research subject group en
Biomedical engineering
Research subject group fr
Biomedical materials
Research subject en
Génie biomédical
Research subject fr
Matériaux biomédicaux
Application title
Nanofreeze Solutions for Organoids and Genetic Material Storage
Keyword
biocompatible; Cell storage; cryopreservation; DMSO free; genetic material storage; nanogels; non toxic; tissue storage
Application summary
This project aims to develop new methods for prolonged storage of tissues and genetic materials. The storage of cells, tissues and genetic material is desirable to improve human health, for biobanking and to develop assisted reproductive technology methods. However, current methods being used for storage of tissues and genetic material involve chemical that can cause toxicity and change the genetic profile of stored materials. Therefore, there is a need to find alternative methods that are non-toxic and inert and can be used for storage of tissues and genetic materials for health applications. We have recently developed a vitamin B5 based technology that has shown excellent capacity to store mammalian cells under freezing conditions. In this project, we will optimize this technology further to produce formulations that can successfully store genetic materials and tissues for various applications.