Grant: Research Tools and Instruments - Category 1 (<$150,000)
University of Western Ontario
$95,000.00
Multiple peptide synthesizer for biochemical and biophysical studies
EF 2010-11
Résumé
This grant application is for the acquisition a Multiple Peptide Synthesizer. This instrument will allow for the cost efficient preparation of large number of synthetic peptides that will be used for various types of biochemical and biophysical experiments.
One principal use of these peptides will be as references to detect low abundance peptides present in biological samples by a mass spectrometry technique called selected reaction monitoring (SRM). Another use will for studying the interactions for proteins with their peptide ligands. Finally, the instrument will be used to prepare peptides to study the substrate specificity for phosphorylation by various kinases.
Dr Lajoie is an expert in peptide chemistry and proteomics. The co-applicants, Drs Konermann, Yeung and Postovit are expert in related fields and are from the Departments of Biochemistry, Chemistry and Cell biology and have a track record of collaborative research.
Programme
Research Tools and Instruments - Category 1 (<$150,000)
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data
Tel que publié
Application id
406128-2011
Name nom
Lajoie, Gilles
Department département
Biochemistry
Organization id
36
Institution établissement
University of Western Ontario
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2010
Competition year année de concours
2011
Award amount
95000
Program id
EQPEQ
Program name en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1504
Committee name en
Chemistry
Committee name fr
Chimie
Area of application code
1201
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Life sciences (including biotechnology)
Area of application fr
Sciences de la vie (y compris biotechnologie)
Research subject code
3504
Research subject group en
Analytical chemistry
Research subject group fr
Chimie analytique
Research subject en
Bioanalytical chemistry
Research subject fr
Chimie bioanalytique
Partie
1
Nb partie
1
Application title
Multiple peptide synthesizer for biochemical and biophysical studies
Keyword
NSERC
Application summary
This grant application is for the acquisition a Multiple Peptide Synthesizer. This instrument will allow for the cost efficient preparation of large number of synthetic peptides that will be used for various types of biochemical and biophysical experiments.
One principal use of these peptides will be as references to detect low abundance peptides present in biological samples by a mass spectrometry technique called selected reaction monitoring (SRM). Another use will for studying the interactions for proteins with their peptide ligands. Finally, the instrument will be used to prepare peptides to study the substrate specificity for phosphorylation by various kinases.
Dr Lajoie is an expert in peptide chemistry and proteomics. The co-applicants, Drs Konermann, Yeung and Postovit are expert in related fields and are from the Departments of Biochemistry, Chemistry and Cell biology and have a track record of collaborative research.