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Grant: Applied Research and Development Grants - Level 1

Lambton College of Applied Arts and Technology

$25,000.00

Design and Optimization of Pre-Packed Column for Pharmaceutical and Biotechnology Applications

EF 2018-19

Résumé
The pharmaceutical and biotechnology industry is moving away from packing columns in-house and towards pre-packed disposable columns due to factors including, lowering the liability on biotechnology companies, decreasing the possibility of contamination, and increasing the consistency of products. The current global market for pre-packed column is projected to reach $1.5 Billion USD by 2019.*PolyAnalytik Inc. is a London-Based company who offers expert analytical support through contract analysis, method development and validation services to petrochemical, polymer/plastics, pharmaceutical companies and research institutions. *Polyanalytik is a leader in chromatographic techniques and method development. Chromatography is a well-established and valuable technique for separating chemical and biological substances and is widely used in research and industry, finding many applications in compound preparation, purification and analysis. There are many different forms of chromatography, column chromatography being of particular importance in the chemical pharmaceutical and biological industries. Numerous factors in the physical orientation of the column and packing of the resin bed are critical to the success of the separation of substances when using a chromatography column. Polyanalytik has spent years studying the problems and experimenting with different solutions to these problems and in doing so, Polyanalytik has come up with a preliminary design for pre-packed columns, which will be studied in this project.*The goal of this project will be to finalize the design of Polyanalytik's pre-packed column and build a prototype for testing. There will be several steps including design fabrication and testing. Once the prototype is built, the unit needs to be tested with various packing material and run under real world conditions to study various conditions and performance. This will allow Polyanalytik to bring to market a novel technology that would increase revenue and create the need to hire additional staff. *
Programme
Applied Research and Development Grants - Level 1
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
522752-2017
Name nom
Sheikhzadeh, Mehdi
Department département
Head Office
Organization id
26621
Institution établissement
Lambton College of Applied Arts and Technology
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2018
Competition year année de concours
2017
Award amount
25000
Program id
CARD1
Program name en
Applied Research and Development Grants - Level 1
Program name fr
Subventions de recherche et développement appliquée - niveau 1
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1561
Committee name en
Applied Research and Development Grants
Committee name fr
Subventions de recherche et développement appliquée
Area of application code
500
Area of application group en
Manufacturing processes and products
Area of application group fr
Procédés et produits industriels
Area of application en
Manufacturing processes and products
Area of application fr
Procédés et produits industriels
Research subject code
1700
Research subject group en
Design and manufacturing
Research subject group fr
Conception et fabrication
Research subject en
Design and manufacturing
Research subject fr
Conception et fabrication
Partie
1
Nb partie
1
Application title
Design and Optimization of Pre-Packed Column for Pharmaceutical and Biotechnology Applications
Keyword
NSERC
Application summary
The pharmaceutical and biotechnology industry is moving away from packing columns in-house and towards pre-packed disposable columns due to factors including, lowering the liability on biotechnology companies, decreasing the possibility of contamination, and increasing the consistency of products. The current global market for pre-packed column is projected to reach $1.5 Billion USD by 2019.*PolyAnalytik Inc. is a London-Based company who offers expert analytical support through contract analysis, method development and validation services to petrochemical, polymer/plastics, pharmaceutical companies and research institutions. *Polyanalytik is a leader in chromatographic techniques and method development. Chromatography is a well-established and valuable technique for separating chemical and biological substances and is widely used in research and industry, finding many applications in compound preparation, purification and analysis. There are many different forms of chromatography, column chromatography being of particular importance in the chemical pharmaceutical and biological industries. Numerous factors in the physical orientation of the column and packing of the resin bed are critical to the success of the separation of substances when using a chromatography column. Polyanalytik has spent years studying the problems and experimenting with different solutions to these problems and in doing so, Polyanalytik has come up with a preliminary design for pre-packed columns, which will be studied in this project.*The goal of this project will be to finalize the design of Polyanalytik's pre-packed column and build a prototype for testing. There will be several steps including design fabrication and testing. Once the prototype is built, the unit needs to be tested with various packing material and run under real world conditions to study various conditions and performance. This will allow Polyanalytik to bring to market a novel technology that would increase revenue and create the need to hire additional staff. *