Grant: Operating Grant: Data Analysis Using Existing Databases and Cohorts
Centre hospitalier de l'Université de Montréal (CHUM)
$99,976.00
Lifestyle and environmental factors, DNA methylation and lung cancer risk
EF 2018-19
Résumé
In Canada, lung cancer is the most deadly cancer among men and women. This research is interested in epigenetics, changes in DNA that controls cellular function, in the development of lung cancer. DNA methylation is a common element of epigenetics, which simply describes a modified form of DNA typically associated with regulating the expression of a gene and/or the stability of our chromosomes. It is thought that many lifestyle and environmental factors can change methylation patterns and that altered levels of DNA methylation is an early event that occurs in the development of cancer. This study proposes to examine the relationships between lifestyle and environmental factors, DNA methylation measured in blood and the development of lung cancer, among participants of the CARTaGENE study, the Québec component of the Canadian Partnership for Tomorrow Project.
Programme
Operating Grant: Data Analysis Using Existing Databases and Cohorts
Emplacement
Quebec, Canada
Type de bénéficiaire
Not-for-profit organization or charity
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
391428
Name
Ho Vikki
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Social / Cultural / Environmental / Population Health
Prcname2
Data Analysis Using Existing Databases and Cohorts
Projecttitle
Lifestyle and environmental factors, DNA methylation and lung cancer risk
Programtype2
Operating Grants
Orgnameinp2
Centre hospitalier de l'Université de Montréal (CHUM)
Cihramount2
$99,976
Cihrequipment2
$0
Programname2
Operating Grant: Data Analysis Using Existing Databases and Cohorts
Keyworddelim
Biomarkers; Dna Methylation; Etiologic Research; Lung Cancer; Molecular Epidemiology; Occupational Exposures; Prevention; Smoking
Abstract
In Canada, lung cancer is the most deadly cancer among men and women. This research is interested in epigenetics, changes in DNA that controls cellular function, in the development of lung cancer. DNA methylation is a common element of epigenetics, which simply describes a modified form of DNA typically associated with regulating the expression of a gene and/or the stability of our chromosomes. It is thought that many lifestyle and environmental factors can change methylation patterns and that altered levels of DNA methylation is an early event that occurs in the development of cancer. This study proposes to examine the relationships between lifestyle and environmental factors, DNA methylation measured in blood and the development of lung cancer, among participants of the CARTaGENE study, the Québec component of the Canadian Partnership for Tomorrow Project.
Competitiondate
201810
Approvedterm2
1 yr 0 mth
Pinamesdelim
Ho, Vikki; Koushik, Anita
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Cancer Research~ $99,976~ $0~
