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Grant: Alliance Grants

York University

$146,000.00

Design, development, and validation of an end-user assay for low-cost, on-site, and rapid quantification of COVID-19 antigen and antibodies

EF 2022-23

Résumé
Introduction of COVID-19 vaccines in late 2020 created hope for overcoming the pandemic, but soon it became clear that mankind is expected to struggle with SARS-CoV-2 until a time when world population (including children) is mass immunized. Reaching this goal is expected to take several years during which: 1) the vaccinated population need to maintain their immunity; 2) more effective approaches (e.g., low-cost, accessible, accurate) should be implemented for earlier identification of infected individuals to prevent future infection peaks. Successful implementation of these two objectives requires population-wide serological studies which in practice can only be realized through low-cost and widely accessible technologies for sensitive detection and quantification of COVID-19 antibodies (Ab) and virus/antigen (Ag). Such technologies currently do not exist.The goal of this partnership is to design, develop, and validate a low-cost end-user rapid test technology for sensitive detection and quantification of COVID-19 antibodies and antigen/virus. The engineering knowledge and innovative technologies generated through this project will enable the government of Canada to implement large scale, accessible and equitable quantitative testing through which well-educated decisions and policies can be made. For Canadian businesses, proposed project provides employers with low-cost, yet accurate, solutions to ensure workplace safety either through sensitive detection of infected individuals, or through monitoring of antibody levels of vaccinated employees. In terms of economy, proposed project aims to solve an existing worldwide challenge with significant socio-economic impact. Given the track record of partner in development and global marketing of rapid tests, the technology to be developed in Canada is expected to make significant contribution to Canadian economy through creation of jobs and global sales.
Programme
Alliance Grants
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
NSERC's Awards Data

Tel que publié

Application id
570531-2021
Name nom
Tabatabaei, Nima N
Department département
Mechanical Engineering
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2022
Competition year année de concours
2021
Award amount
146000
Program id
ALLRP
Program name en
Alliance Grants
Program name fr
Subventions Alliance
Group en
RESEARCH PARTNERSHIPS
Group fr
PARTENARIATS DE RECHERCHE
Committee code
96
Committee name en
RPP Internal Decision Cttee
Committee name fr
Cté de décision interne - PPR
Area of application code
1101
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Human health (including medically-related psychological research)
Area of application fr
Santé publique (y compris recherche psychologique liée à la médecine)
Research subject code
1901
Research subject group en
Biomedical engineering
Research subject group fr
Génie biomédical
Research subject en
Biomedical technology
Research subject fr
Technologie biomédicale
Installment
inst:2
Partie
1
Nb partie
2
Application title
Design, development, and validation of an end-user assay for low-cost, on-site, and rapid quantification of COVID-19 antigen and antibodies
Application summary
Introduction of COVID-19 vaccines in late 2020 created hope for overcoming the pandemic, but soon it became clear that mankind is expected to struggle with SARS-CoV-2 until a time when world population (including children) is mass immunized. Reaching this goal is expected to take several years during which: 1) the vaccinated population need to maintain their immunity; 2) more effective approaches (e.g., low-cost, accessible, accurate) should be implemented for earlier identification of infected individuals to prevent future infection peaks. Successful implementation of these two objectives requires population-wide serological studies which in practice can only be realized through low-cost and widely accessible technologies for sensitive detection and quantification of COVID-19 antibodies (Ab) and virus/antigen (Ag). Such technologies currently do not exist.The goal of this partnership is to design, develop, and validate a low-cost end-user rapid test technology for sensitive detection and quantification of COVID-19 antibodies and antigen/virus. The engineering knowledge and innovative technologies generated through this project will enable the government of Canada to implement large scale, accessible and equitable quantitative testing through which well-educated decisions and policies can be made. For Canadian businesses, proposed project provides employers with low-cost, yet accurate, solutions to ensure workplace safety either through sensitive detection of infected individuals, or through monitoring of antibody levels of vaccinated employees. In terms of economy, proposed project aims to solve an existing worldwide challenge with significant socio-economic impact. Given the track record of partner in development and global marketing of rapid tests, the technology to be developed in Canada is expected to make significant contribution to Canadian economy through creation of jobs and global sales.