Grant: Planning and Dissemination Grant - Institute Community Support

Background: Injuries to bones, muscles, and joints are common, but treatments can sometimes fall short of helping patients recover fully. Peptides-tiny protein-like molecules-have shown promise in promoting healing and tissue repair. Over recent years, researchers have found that certain synthetic peptides may boost the body's ability to heal and regenerate musculoskeletal tissues, making them an exciting area of study for future medical treatments. Methods: This planning project focuses on laying the groundwork for future clinical trials to explore how these peptides might help improve recovery for patients with musculoskeletal injuries. First, we will carefully review all existing research on peptides and their role in healing and regeneration. Using this information, we will bring together experts from different fields to form a collaborative research group. This group will analyze the data and use a structured process to decide on the most promising peptides to test and the key outcomes to measure in future studies. Finally, we will develop a detailed plan for a small clinical trial to test the safety and feasibility of using these peptides in patients. This trial will help us understand whether the peptides are safe and effective enough to warrant larger studies in the future. Conclusions: By bringing together Canada's top researchers and focusing on innovative solutions, this project aims to take the first steps toward new treatments that could transform how we care for injuries to bones, muscles, and joints. These advances could make recovery faster, easier, and more effective for patients and clinicians alike.