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Grant: Operating Grant

Research Institute of the McGill University Health Centre

$321,624.00

Characterization and efficacy of bisphosphonate eluting orthopaedic implants

EF 2008-09

Résumé
Many joint replacement devices are attached directly to bone by encouraging bone formation in and around the implant surface. The use of drugs such as bisphosphponates that enhance local bone formation would improve the efficacy and longevity of implant fixation. Attaching bisphosphonate compounds directly to an implant for progressive release to surrounding bone is a simple and effective means to achieve this goal.
Programme
Operating Grant
Emplacement
Quebec, Canada
Type
Grant
Source
CIHR Funding Decisions Database

Tel que publié

Id
171491
Name
Bobyn John D
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Musculoskeletal Health and Arthritis
Theme2
Biomedical
Prcname2
Biomedical Engineering
Projecttitle
Characterization and efficacy of bisphosphonate eluting orthopaedic implants
Programtype2
Operating Grants
Orgnameinp2
Research Institute of the McGill University Health Centre
Cihramount2
$321,624
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Drug Release; Histology; Implant Fixation; Joint Replacement; Peri-Implant Bone Formation; Porous Biomaterials
Abstract
Many joint replacement devices are attached directly to bone by encouraging bone formation in and around the implant surface. The use of drugs such as bisphosphponates that enhance local bone formation would improve the efficacy and longevity of implant fixation. Attaching bisphosphonate compounds directly to an implant for progressive release to surrounding bone is a simple and effective means to achieve this goal.
Competitiondate
200809
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Bobyn, John D; Tanzer, Michael
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $321,624~ $0~