Grant: Project Grant
Queen's University (Kingston, Ontario)
$1,181,926.00
Extracellular Vesicles are the Gatekeepers of the Haematopoietic Stem Cell Health and Survival
EF 2025-26
Résumé
Population aging is one of society's urgent challenges. Aging increases your propensity to developing many diseases such as cancer. Haematopoietic stem cells (HSCs) are extremely important for a healthy life as they are responsible for producing all blood and immune cells that we require everyday. Haematopoietic stem cells reside within our bones, where they are kept in a protective environment. Our group will investigate extracellular vesicles (EVs) within the bone. EVs are tiny nanoparticles that contain lipid, nucleic acid and proteins, and are thought to facilitate communication between cells. Our goal is to understand the changes that occur during aging and if EVs play a role in cancer development.
Programme
Project Grant
Bénéficiaire
Emplacement
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
565951
Name
Abraham Sheela A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cancer Biology & Therapeutics 2
Projecttitle
Extracellular Vesicles are the Gatekeepers of the Haematopoietic Stem Cell Health and Survival
Programtype2
Operating Grants
Orgnameinp2
Queen's University (Kingston, Ontario)
Cihramount2
$1,181,926
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Aging; Extracellular Vesicles; Haematopoietic Stem Cells; Pre-Leukaemia
Abstract
Population aging is one of society's urgent challenges. Aging increases your propensity to developing many diseases such as cancer. Haematopoietic stem cells (HSCs) are extremely important for a healthy life as they are responsible for producing all blood and immune cells that we require everyday. Haematopoietic stem cells reside within our bones, where they are kept in a protective environment. Our group will investigate extracellular vesicles (EVs) within the bone. EVs are tiny nanoparticles that contain lipid, nucleic acid and proteins, and are thought to facilitate communication between cells. Our goal is to understand the changes that occur during aging and if EVs play a role in cancer development.
Competitiondate
202603
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Abraham, Sheela A
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $1,181,926~ $0~
