Grant: Op. Gr.: Addr. Wider Impacts of COVID-Imp. on social/econ/pop iss/pbl outcomes
University of Calgary
$455,834.00
Addressing rising Canadian radon gas-induced lung cancer risk due to COVID-19 pandemic-linked lung injury, disability, and behaviour change
EF 2021-22
Résumé
Our goal is to understand and address rising radon gas-induced lung cancer risks due to COVID-19 pandemic-linked lung injury, disability, and behaviour change. 1 in 5 lung cancers arise in Canadians who have never smoked, with ~110,000 cases since 2001. A previous lung disease history is directly associated with increased lung cancer risk in never-smokers, making them more vulnerable to triggers. The most common lung cancer trigger in never-smokers is repetitive inhalation of radioactive radon gas, a prevalent carcinogen in the Canadian residential environment that emits highly mutagenic particle radiation.
The amount of life spent 'at home' correlates with radon exposure, modifying lung cancer risk as a function of our behaviour and built environment. Young people and the 6 million Canadians living with disability were, even before the pandemic, exposed to more radon due to biases in how they are able access housing stock. Today, fully 1 in 5 people hospitalized with COVID-19 are returning to their lives with a new disability, as lung and heart injury increases prevalence of debilitating fatigue, cognitive impairment, and reduced mobility; collectively, these alter employment prospects, behaviour, and time spent at home. For others, COVID-19-related behaviour changes such as heightened demand for long term telecommuting is changing radon exposure, with a 20% increase in particle radiation dose to lungs recorded for 18-45 year-olds so far.
In this project, we will (1) measure radon exposure of Canadians experiencing COVID-19-induced disability and/or behaviour change, as a function of personal demographics, employment sector, job profile and across the built environment; (2) estimate radon-induced lung cancer burdens and costs in a pandemic-modified future with/without intervention for impacted groups; and (3) develop, for the first time, radon reduction resources for those living with disability, with a focus on COVID-19 survivors and promoting healthier cities.
Programme
Op. Gr.: Addr. Wider Impacts of COVID-Imp. on social/econ/pop iss/pbl outcomes
Bénéficiaire
Emplacement
Alberta, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
CIHR Funding Decisions Database
Tel que publié
Id
460291
Name
Goodarzi Aaron
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Social / Cultural / Environmental / Population Health
Prcname2
Operating Grant : Addressing the Wider Health Impacts of COVID-
Projecttitle
Addressing rising Canadian radon gas-induced lung cancer risk due to COVID-19 pandemic-linked lung injury, disability, and behaviour change
Programtype2
Operating Grants
Orgnameinp2
University of Calgary
Cihramount2
$455,834
Cihrequipment2
$0
Programname2
Op. Gr.: Addr. Wider Impacts of COVID-Imp. on social/econ/pop iss/pbl outcomes
Keyworddelim
Behaviour Change; Built Environment; Covid-19; Disability; Healthy Cities; Lung Cancer; Lung Injury; Radiation Dosimetry; Radon Gas; Telecommuting
Abstract
Our goal is to understand and address rising radon gas-induced lung cancer risks due to COVID-19 pandemic-linked lung injury, disability, and behaviour change. 1 in 5 lung cancers arise in Canadians who have never smoked, with ~110,000 cases since 2001. A previous lung disease history is directly associated with increased lung cancer risk in never-smokers, making them more vulnerable to triggers. The most common lung cancer trigger in never-smokers is repetitive inhalation of radioactive radon gas, a prevalent carcinogen in the Canadian residential environment that emits highly mutagenic particle radiation.
The amount of life spent 'at home' correlates with radon exposure, modifying lung cancer risk as a function of our behaviour and built environment. Young people and the 6 million Canadians living with disability were, even before the pandemic, exposed to more radon due to biases in how they are able access housing stock. Today, fully 1 in 5 people hospitalized with COVID-19 are returning to their lives with a new disability, as lung and heart injury increases prevalence of debilitating fatigue, cognitive impairment, and reduced mobility; collectively, these alter employment prospects, behaviour, and time spent at home. For others, COVID-19-related behaviour changes such as heightened demand for long term telecommuting is changing radon exposure, with a 20% increase in particle radiation dose to lungs recorded for 18-45 year-olds so far.
In this project, we will (1) measure radon exposure of Canadians experiencing COVID-19-induced disability and/or behaviour change, as a function of personal demographics, employment sector, job profile and across the built environment; (2) estimate radon-induced lung cancer burdens and costs in a pandemic-modified future with/without intervention for impacted groups; and (3) develop, for the first time, radon reduction resources for those living with disability, with a focus on COVID-19 survivors and promoting healthier cities.
Competitiondate
202111
Approvedterm2
2 yrs 0 mth
Pinamesdelim
Goodarzi, Aaron
Approvedterm
2 ans 0 mois
Cihrcontribution2
~ $455,834~ $0~