Contribution: Industrial Research Assistance Program – Contributions to Firms
ProteinQure Inc.
$206,800.00
In vivo validation of ProteinQure’s SORT1 delivery platform for triple negative breast cancer in patient relevant Trodelvy resistant animal models
EF 2023-24 · 2023-08-16
Résumé
ProteinQure is going to show the potential of its SORT1 delivery platform by demonstrating the ability to cure Trodelvy/Enhertu resistant Triple Negative Breast Cancer (the most deadly form of breast cancer with no treatments). This IRAP project will involve the design and creation of animal models based on patient samples (PDX) which recapitulate acquired resistance to Trodelvy/Enhertu. While simpler PDX models would be sufficient for regulatory purposes, more advanced models increase the commercial potential and likelihood of success for the SORT1 platform in TNBC.
Ministère
Programme
Industrial Research Assistance Program – Contributions to FirmsIndustrial Research Assistance Program-Contributions to Firms (lien de confiance élevée)
Bénéficiaire
Emplacement
Toronto|Toronto, Ontario, Canada
Type de bénéficiaire
For-profit organization
Numéro d'entreprise
788609683
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
Tel que publié
Agreement End Date
2024-04-30
Agreement Number
1010963
Agreement Start Date
2023-08-16
Agreement Title
In vivo validation of ProteinQure’s SORT1 delivery platform for triple negative breast cancer in patient relevant Trodelvy resistant animal models
Agreement Title (French)
Validation in vivo de la plateforme SORT1 de ProteinQure pour le cancer du sein triple négatif dans des modèles animaux résistants au Trodelvy et adaptés aux patients.
Agreement Type
Contribution
Agreement Value
$206,800.00
Amendment Number
0
Coverage
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation. | Les projets des Contributions aux entreprises stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
ProteinQure is going to show the potential of its SORT1 delivery platform by demonstrating the ability to cure Trodelvy/Enhertu resistant Triple Negative Breast Cancer (the most deadly form of breast cancer with no treatments). This IRAP project will involve the design and creation of animal models based on patient samples (PDX) which recapitulate acquired resistance to Trodelvy/Enhertu. While simpler PDX models would be sufficient for regulatory purposes, more advanced models increase the commercial potential and likelihood of success for the SORT1 platform in TNBC.
Description (French)
ProteinQure va démontrer le potentiel de sa plateforme SORT1 en démontrant sa capacité à guérir le cancer du sein triple négatif résistant au Trodelvy/Enhertu (la forme de cancer du sein la plus mortelle pour laquelle il n’existe aucun traitement). Ce projet du PARI impliquera la conception et la création de modèles animaux basés sur des échantillons de patients (PDX) qui récapitulent la résistance acquise au Trodelvy/Enhertu. Alors que des modèles PDX plus simples seraient suffisants à des fins réglementaires, des modèles plus avancés augmentent le potentiel commercial et les chances de succès de la plateforme SORT1 dans le TNBC.
Expected Results
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Expected Results (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Federal Riding
Spadina--Fort York
Federal Riding (French)
Spadina--Fort York
Federal Riding Number
35101
NAICS Code
325410
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Contributions to Firms
Program Name (French)
Programme d’aide à la recherche industrielle – Contributions aux entreprises
Program Purpose
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Program Purpose (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Recipient Business Number
788609683
Recipient City
Toronto|Toronto
Recipient Country
CA
Recipient Legal Name
ProteinQure Inc.
Recipient Postal Code
M5V 2L1
Recipient Province or Territory
ON
Recipient Type
F
Reference Number
172-2023-2024-Q3-1010963
