Grant: Strategic Projects - Group
Liu, Juewen (University of Waterloo)
$593,025.00
DNA-gated stimuli-responsive nanostructures for metal sensing and smart remediation
EF 2017-18 · 2017-10-18
Résumé
Around 40% of the rivers and lakes in America are polluted, and this problem is much more serious in developing countries. In particular, water contamination by heavy metals is a growing problem with serious adverse health effects. Therefore, detection and remediation of heavy metals is a major task for analytical chemists and environmental engineers. We propose herein a biomimetic device for solving this problem. The device releases sensing or remediation chemicals only in the presence of target contaminants, while it can stably flow in water for a long time in a benign polymer capsule in the absence the target. Our approach will change the sampling-testing-remediation method to the new seeking-responding-remediation (SRR). To achieve this goal, we propose to use DNAzyme-gated polymersomes for searching contaminants and remediation. Compared to dumping chemicals into water for remediation, our approach is more targeted with a higher efficiency. This project will be performed with our collaborator in the University of Bordeaux in France through NSERC's international collaboration program. Two local Canadian companies will also be involved to guide the project to make practical impacts.
Programme
Strategic Projects - Group
Bénéficiaire
Emplacement
Ontario, Canada
Type de bénéficiaire
Academia
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
Tel que publié
Additional Information
Grant or Award spanning more than one fiscal year (2017-2018 to 2020-2021).
Additional Information (French)
Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2020-2021).
Agreement Number
STPGP
Agreement Start Date
2017-10-18
Agreement Title
DNA-gated stimuli-responsive nanostructures for metal sensing and smart remediation
Agreement Title (French)
DNA-gated stimuli-responsive nanostructures for metal sensing and smart remediation
Agreement Type
Grant
Agreement Value
$593,025.00
Amendment Number
0
Organization Code
nserc-crsng
Organization
Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada
Program Name
Strategic Projects - Group
Program Name (French)
Projets stratégiques - groupe
Program Purpose
Around 40% of the rivers and lakes in America are polluted, and this problem is much more serious in developing countries. In particular, water contamination by heavy metals is a growing problem with serious adverse health effects. Therefore, detection and remediation of heavy metals is a major task for analytical chemists and environmental engineers. We propose herein a biomimetic device for solving this problem. The device releases sensing or remediation chemicals only in the presence of target contaminants, while it can stably flow in water for a long time in a benign polymer capsule in the absence the target. Our approach will change the sampling-testing-remediation method to the new seeking-responding-remediation (SRR). To achieve this goal, we propose to use DNAzyme-gated polymersomes for searching contaminants and remediation. Compared to dumping chemicals into water for remediation, our approach is more targeted with a higher efficiency. This project will be performed with our collaborator in the University of Bordeaux in France through NSERC's international collaboration program. Two local Canadian companies will also be involved to guide the project to make practical impacts.
Program Purpose (French)
Around 40% of the rivers and lakes in America are polluted, and this problem is much more serious in developing countries. In particular, water contamination by heavy metals is a growing problem with serious adverse health effects. Therefore, detection and remediation of heavy metals is a major task for analytical chemists and environmental engineers. We propose herein a biomimetic device for solving this problem. The device releases sensing or remediation chemicals only in the presence of target contaminants, while it can stably flow in water for a long time in a benign polymer capsule in the absence the target. Our approach will change the sampling-testing-remediation method to the new seeking-responding-remediation (SRR). To achieve this goal, we propose to use DNAzyme-gated polymersomes for searching contaminants and remediation. Compared to dumping chemicals into water for remediation, our approach is more targeted with a higher efficiency. This project will be performed with our collaborator in the University of Bordeaux in France through NSERC's international collaboration program. Two local Canadian companies will also be involved to guide the project to make practical impacts.
Recipient City
Ontario
Recipient Country
CA
Recipient Legal Name
Liu, Juewen (University of Waterloo)
Reference Number
GC-2017-Q3-00809