Contribution: Industrial Research Assistance Program – Contributions to Firms
Basetwo Artificial Intelligence Inc.
$448,291.00
UK Biomanufacturing -10140856-HMCIBP- Leveraging hybrid digital twins to optimize the control and performance of integrated biomanufacturing processes
EF 2025-26 · 2025-05-01
Résumé
As part of the international consortium project “HMCIBP: Leveraging hybrid digital twins to optimize the control and performance of integrated biomanufacturing processes”, this project will develop a fully integrated, AI-driven bioprocess optimization platform to enhance production efficiency and quality in biopharmaceutical manufacturing. It combines real-time data on cell density, viability, metabolites, and titre—captured via innovative SPR technology—with automated sampling and hybrid model-based control. This integration enables rapid process adjustments for both high-throughput and conventional bioreactors, reducing costs and improving product consistency.
Ministère
Programme
Industrial Research Assistance Program – Contributions to FirmsIndustrial Research Assistance Program-Contributions to Firms (lien de confiance élevée)
Bénéficiaire
Emplacement
Toronto|Toronto, Ontario, Canada
Type de bénéficiaire
For-profit organization
Numéro d'entreprise
753786805
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
Tel que publié
Agreement End Date
2026-12-10
Agreement Number
1031652
Agreement Start Date
2025-05-01
Agreement Title
UK Biomanufacturing -10140856-HMCIBP- Leveraging hybrid digital twins to optimize the control and performance of integrated biomanufacturing processes
Agreement Title (French)
UK Biomanufacturing -10140856-HMCIBP- Exploiter les jumeaux numériques hybrides pour optimiser le contrôle et la performance des processus intégrés de biofabrication
Agreement Type
Contribution
Agreement Value
$448,291.00
Amendment Number
0
Coverage
IRAP Contributions to Firms projects stimulate wealth creation for Canada through technological innovation. | Les projets des Contributions aux entreprises stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
As part of the international consortium project “HMCIBP: Leveraging hybrid digital twins to optimize the control and performance of integrated biomanufacturing processes”, this project will develop a fully integrated, AI-driven bioprocess optimization platform to enhance production efficiency and quality in biopharmaceutical manufacturing. It combines real-time data on cell density, viability, metabolites, and titre—captured via innovative SPR technology—with automated sampling and hybrid model-based control. This integration enables rapid process adjustments for both high-throughput and conventional bioreactors, reducing costs and improving product consistency.
Description (French)
Dans le cadre du projet de consortium international « HMCIBP : Leveraging hybrid digital twins to optimize the control and performance of integrated biomanufacturing processes », ce projet développera une plateforme d’optimisation des bioprocédés entièrement intégrée et pilotée par l’IA afin d’améliorer l’efficacité et la qualité de la production dans la fabrication biopharmaceutique. Cette plateforme combine des données en temps réel sur la densité cellulaire, la viabilité, les métabolites et le titre - capturées par une technologie SPR innovante - avec un échantillonnage automatisé et un contrôle hybride basé sur un modèle. Cette intégration permet d’ajuster rapidement les processus pour les bioréacteurs à haut débit et les bioréacteurs conventionnels, réduisant ainsi les coûts et améliorant la cohérence des produits.
Expected Results
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Expected Results (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Federal Riding
University--Rosedale
Federal Riding (French)
University--Rosedale
Federal Riding Number
35110
NAICS Code
541514
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Contributions to Firms
Program Name (French)
Programme d’aide à la recherche industrielle – Contributions aux entreprises
Program Purpose
The purpose of IRAP Contributions to Firms is to support research, development, adoption and/or adaptation of innovative or technology-driven new or improved products, services or processes in Canada up to their commercialization
Program Purpose (French)
Le PARI, par le biais des Contributions aux entreprises, vise à appuyer la recherche, le développement, l’adaptation et/ou l’adoption au Canada de produits, de services ou de processus novateurs ou axés sur des technologies nouvelles ou améliorées, et ce jusqu’à leur commercialisation
Recipient Business Number
753786805
Recipient City
Toronto|Toronto
Recipient Country
CA
Recipient Legal Name
Basetwo Artificial Intelligence Inc.
Recipient Operating Name
Basetwo Artificial Intelligence Inc.
Recipient Postal Code
M5G 1M1
Recipient Province or Territory
ON
Recipient Type
F
Reference Number
172-2025-2026-Q1-1031652
