Grant: Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
University of Ottawa
$272,030.00
Quantum bio-sensing for next generation health diagnostics
EF 2021-22 · 2021-10-28
Résumé
Technological advances in imaging instrumentation in the near-infrared (NIR) range (1,000-1,700 nm) have resulted in unparalleled improvements in fluorescence image resolution and depth of penetration in biological tissues, required for highly sensitive and selective biosensors and preclinical in vivo imaging. However, one major limitation for the clinical adoption of NIR imaging is the lack of biocompatible and powerful (high quantum yield, high brightness) NIR emitters. Lanthanide-doped nanoparticles (Ln-NPs) constitute an emerging class of nanomaterials with extraordinary potential to drive innovation in biomolecular imaging and quantum chemical sensing. However, the transformation of these Ln-NPs into multi-modal imaging probes, intelligent bio-sensors and theranostic agents requires innovative design engineering based on understanding of their structure-property relationships, biocompatibility, and nano-bio interactions. The Project will lead to the development of powerful bioprobes capable of non-invasive monitoring of biochemical changes and processes deep in the body and in clinical samples.
Ministère
Programme
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Bénéficiaire
Emplacement
Ottawa|Ottawa, Ontario, Canada
Type de bénéficiaire
Academia
Numéro d'entreprise
119278877
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
Modifications
Chaque version de l'entente telle que publiée, de la plus ancienne à la plus récente, avec son total à cette version. Le montant ci-dessus est le plus récent.
| Modification | Date | Exercice financier | Total |
|---|---|---|---|
| 0 | 2021-10-28 | 2021-22 | $272,030.00 |
| 1 | 2021-10-28 | 2021-22 | $272,030.00 |
Tel que publié
Additional Information
This agreement has been amended 1 time(s). The end date of this agreement has been modified by 351 days.
Additional Information (French)
Cet accord a été modifié 1 fois. La date de fin du présent accord a été changé de 351 jours.
Agreement End Date
2025-09-30
Agreement Number
981426
Agreement Start Date
2021-10-28
Agreement Title
Quantum bio-sensing for next generation health diagnostics
Agreement Title (French)
Biodétection quantique pour la prochaine génération de diagnostics médicaux
Agreement Type
Grant
Agreement Value
$272,030.00
Amendment Date
2024-08-22
Amendment Number
1
Description
Technological advances in imaging instrumentation in the near-infrared (NIR) range (1,000-1,700 nm) have resulted in unparalleled improvements in fluorescence image resolution and depth of penetration in biological tissues, required for highly sensitive and selective biosensors and preclinical in vivo imaging. However, one major limitation for the clinical adoption of NIR imaging is the lack of biocompatible and powerful (high quantum yield, high brightness) NIR emitters. Lanthanide-doped nanoparticles (Ln-NPs) constitute an emerging class of nanomaterials with extraordinary potential to drive innovation in biomolecular imaging and quantum chemical sensing. However, the transformation of these Ln-NPs into multi-modal imaging probes, intelligent bio-sensors and theranostic agents requires innovative design engineering based on understanding of their structure-property relationships, biocompatibility, and nano-bio interactions. The Project will lead to the development of powerful bioprobes capable of non-invasive monitoring of biochemical changes and processes deep in the body and in clinical samples.
Description (French)
Biodétection quantique pour la prochaine génération de diagnostics médicaux
Expected Results
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.
Expected Results (French)
À court terme, les résultats prévus seront des collaborations renforcées entre l'industrie, le milieu universitaire et le gouvernement pour soutenir l'excellence en recherche. À moyen terme, les résultats attendus seront le développement de nouvelles technologies potentiellement perturbatrices avec des collaborateurs. À long terme, trouver des solutions collaboratives aux défis des politiques publiques et créer des systèmes d'innovation plus solides.
Federal Riding
Ottawa--Vanier--Gloucester
Federal Riding (French)
Ottawa--Vanier--Gloucester
Federal Riding Number
35081
NAICS Code
541710 - R&D in the physical, engineering and life sciences
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Program Name (French)
Programme de collaboration en science, en technologie et en innovation - Initiatives de collaboration en R-D
Program Purpose
Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.
Program Purpose (French)
Collaborer à des programmes multipartites de recherche-développement dans le but de profiter de la synergie entre la recherche transformatrice à haut risque et à haut rendement et le potentiel de découvertes scientifiques et de percées technologiques révolutionnaires dans des secteurs d’intervention prioritaires.
Recipient Business Number
119278877
Recipient City
Ottawa|Ottawa
Recipient Country
CA
Recipient Legal Name
University of Ottawa
Recipient Postal Code
K1N 6N5
Recipient Province or Territory
ON
Recipient Type
S
Reference Number
172-2021-2022-Q3-981426
